Domperidone

Known as: 1-(3-(4-(5-chloro-2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[D]imidazol-2(3H)-one, 5-chloro-1-(1-(3-(2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[D]imidazol-2(3H)-one, Domperidona 
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
This guideline presents recommendations for the evaluation and management of patients with gastroparesis. Gastroparesis is… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Recently, a 4-fold increase in risk of sudden cardiac death (SCD) was reported for domperidone in a study that focused… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients' quality of… (More)
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Highly Cited
2001
Highly Cited
2001
Background:The efficacy of prokinetic agents in functional (nonulcer) dyspepsia has been questioned based on recent trial results… (More)
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Highly Cited
1999
Highly Cited
1999
Objective:A double-blind, multicenter, randomized trial was conducted to compare the side effects and efficacy of domperidone and… (More)
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Highly Cited
1998
Highly Cited
1998
The purpose of this clinical study was to determine the efficacy, tolerability, and impact on quality of life of domperidone--a… (More)
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Highly Cited
1997
Highly Cited
1997
This study investigated whether domperidone could improve gastrointestinal symptoms in patients with Parkinson's disease who were… (More)
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Highly Cited
1996
Highly Cited
1996
The mouse mdr1a (also called mdr3) P-GP is abundant in the blood-brain barrier, and its absence in mdr1a (-/-) mice leads to… (More)
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Highly Cited
1989
Highly Cited
1989
We measured gastric emptying and gastric myoelectrical activity with solid-phase gastric-emptying tests and cutaneously recorded… (More)
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1984
1984
To study the absorption of levodopa and interaction with the extracerebral dopamine antagonist domperidone, 15 patients with… (More)
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