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Domperidone

Known as: 1-(3-(4-(5-chloro-2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[D]imidazol-2(3H)-one, 5-chloro-1-(1-(3-(2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[D]imidazol-2(3H)-one, Domperidona 
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
This guideline presents recommendations for the evaluation and management of patients with gastroparesis. Gastroparesis is… Expand
Highly Cited
2010
Highly Cited
2010
AbstractBackground: Recently, a 4-fold increase in risk of sudden cardiac death (SCD) was reported for domperidone in a study… Expand
Highly Cited
2009
Highly Cited
2009
Background:  Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients’ quality… Expand
Highly Cited
2007
Highly Cited
2007
There is limited evidence for the treatment of orthostatic hypotension in idiopathic Parkinson's disease. The objective of this… Expand
Highly Cited
2006
Highly Cited
2006
Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients’ quality of life. To… Expand
Highly Cited
1999
Highly Cited
1999
Objective:A double-blind, multicenter, randomized trial was conducted to compare the side effects and efficacy of domperidone and… Expand
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Highly Cited
1996
Highly Cited
1996
The mouse mdr1a (also called mdr3) P-GP is abundant in the blood-brain barrier, and its absence in mdr1a (-/-) mice leads to… Expand
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Highly Cited
1989
Highly Cited
1989
We measured gastric emptying and gastric myoelectrical activity with solid-phase gastric-emptying tests and cutaneously recorded… Expand
Highly Cited
1987
Highly Cited
1987
1. Intracellular recordings were made from neurones in the substantia nigra zona compacta in slices of rat mesencephalon in vitro… Expand
Highly Cited
1979
Highly Cited
1979
When tested in different in vitro binding assays and in dopamine-sensitive adenylate cyclase, domperidone was found to be a very… Expand