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Domperidone

Known as: 1-(3-(4-(5-chloro-2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[D]imidazol-2(3H)-one, 5-chloro-1-(1-(3-(2-oxo-2,3-Dihydrobenzo[D]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[D]imidazol-2(3H)-one, Domperidona 
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the… 
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (11)

5-fluoro-2-indolyldeschlorohalopemideDomperidon HexalDomperidona GamirDomperidone maleate

Broader (2)

AntiemeticsDopamine Antagonists
CYP3A7 protein, humanDomperidone 10 MGIn Bloodagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Formulation and in vitro characterization of domperidone loaded solid lipid nanoparticles and nanostructured lipid carriers
Background and the purpose of the study Domperidone (DOM) is a dopamine- receptor (D2) antagonist, widely used in the treatment… 
Highly Cited
2005
Highly Cited
2005
Enhancing spawning in the grey mullet (Mugil cephalus) by removal of dopaminergic inhibition.
Highly Cited
1999
Highly Cited
1999
A double-blind multicenter comparison of domperidone and metoclopramide in the treatment of diabetic patients with symptoms of gastroparesisFig. 1
Objective:A double-blind, multicenter, randomized trial was conducted to compare the side effects and efficacy of domperidone and… 
Review
1997
Review
1997
Gastrointestinal Motility Problems in Patients with Parkinson’s Disease
SummaryGastrointestinal (GI) motility disorders are frequent in patients with Parkinson’s disease, manifesting mainly as… 
Highly Cited
1997
Highly Cited
1997
Effect of chronic oral domperidone therapy on gastrointestinal symptoms and gastric emptying in patients with parkinson's disease
This study investigated whether domperidone could improve gastrointestinal symptoms in patients with Parkinson's disease who were… 
Highly Cited
1992
Highly Cited
1992
Characterization of big, big prolactin in patients with hyperprolactinaemia
OBJECTIVE The present study was designed to characterize the clinical findings of patients with macroprolactin‐aemia (sustained… 
Highly Cited
1990
Highly Cited
1990
Pituitary site of action of endothelin: selective inhibition of prolactin release in vitro.
Highly Cited
1987
Highly Cited
1987
Dopamine inhibits cytosolic Ca2+ increases in rat lactotroph cells. Evidence of a dual mechanism of action.
Highly Cited
1987
Highly Cited
1987
Excitatory and inhibitory effects of dopamine on neuronal activity of the caudate nucleus neurons in vitro
Highly Cited
1984
Highly Cited
1984
The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity.
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