• Publications
  • Influence
Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation.
Helicobacter pylori adherence in the human gastric mucosa involves specific bacterial adhesins and cognate host receptors. Here, we identify sialyl-dimeric-Lewis x glycosphingolipid as a receptor forExpand
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Role of ABO Secretor Status in Mucosal Innate Immunity and H. pylori Infection
The fucosylated ABH antigens, which constitute the molecular basis for the ABO blood group system, are also expressed in salivary secretions and gastrointestinal epithelia in individuals of positiveExpand
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SabA Is the H. pylori Hemagglutinin and Is Polymorphic in Binding to Sialylated Glycans
Adherence of Helicobacter pylori to inflamed gastric mucosa is dependent on the sialic acid–binding adhesin (SabA) and cognate sialylated/fucosylated glycans on the host cell surface. By in situExpand
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Helicobacter pylori is invasive and it may be a facultative intracellular organism
The pathogenicity of many bacteria colonizing the gastrointestinal tract often depends on their ability to gain access to cells that are normally non‐phagocytic. Helicobacter pylori colonizes theExpand
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Helicobacter pylori SabA Adhesin in Persistent Infection and Chronic Inflammation
Helicobacter pylori adherence in the human gastric mucosa involves specific bacterial adhesins and cognate host receptors. Here, we identify sialyl-dimeric-Lewis x glycosphingolipid as a receptor forExpand
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Intracellular and interstitial expression of Helicobacter pylori virulence genes in gastric precancerous intestinal metaplasia and adenocarcinoma.
Gastric intestinal metaplasia (IM) and gastric cancer are associated with Helicobacter pylori, but the bacterium often is undetectable in these lesions. To unravel this apparent paradox, IM, H.Expand
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Gastrointestinal dysfunction in systemic mastocytosis. A prospective study.
In 16 consecutive patients with systemic mastocytosis, we prospectively evaluated a variety of gastrointestinal functions and examined how they relate to the occurrence of gastrointestinal symptoms.Expand
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Host specificity of Helicobacter pylori strains and host responses in experimentally challenged nonhuman primates.
BACKGROUND & AIMS The specificity of colonization by Helicobacter pylori and complex host-bacterium interactions cannot be readily examined in humans. The aim of this study was to perform suchExpand
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Spiral bacteria in the human stomach: the gastric helicobacters.
  • A. Dubois
  • Medicine
  • Emerging infectious diseases
  • 1 July 1995
During the past decade, Helicobacter pylori has become recognized as one of the most common human pathogens, colonizing the gastric mucosa of almost all persons exposed to poor hygienic conditionsExpand
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Detailed In Vivo Analysis of the Role of Helicobacter pylori Fur in Colonization and Disease
ABSTRACT Helicobacter pylori persistently colonizes the harsh and dynamic environment of the stomach in over one-half of the world's population and has been identified as a causal agent in a spectrumExpand
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