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Disintegrant Excipient

Known as: Disintegrant 
Disintegrant excipient is a therapeutically inactive ingredient of a solid pharmaceutical dosage form that helps the form to dissolve within the… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
A comparative study of the utility of two superdisintegrants in microcrystalline cellulose pellets prepared by extrusion-spheronization.
2003
2003
Biphasic drug release from film-coated tablets.
2001
2001
Influence of binder properties, method of addition, powder type and operating conditions on fluid-bed melt granulation and resulting tablet properties.
The aim of the study was to investigate melt granulation in a laboratory scale fluid-bed granulator with respect to granule… 
1999
1999
An in vitro investigation into the potential for bimodal drug release from pectin/chitosan/HPMC-coated tablets.
1987
1987
Enhancement of the dissolution rate of a poorly water‐soluble drug (tolbutamide) by a spray‐drying solvent deposition method and disintegrants
The dissolution rate of a poorly water‐soluble drug, tolbutamide, was improved by spray‐drying a diluted ammonia solution of the… 
1987
1987
Effect of tablet solubility and hygroscopicity on disintegrant efficiency in direct compression tablets in terms of dissolution.
The effect of tablet composite solubility and hygroscopicity on the dissolution efficiency of three "super disintegrants", sodium… 
1986
1986
Drug-excipient interactions resulting from powder mixing. III: Solid state properties and their effect on drug dissolution.
Micronized prednisone was used to study the effect of powder mixing on drug-excipient interactions and their effect on in vitro… 
1980
1980
Simplex search in optimization of capsule formulation.
The simplex method of optimization was applied to a capsule formulation uing the dissolution rate and compaction rate as the… 
1978
1978
Factors affecting the disintegration and dissolution of chloroquine phosphate/starch tablets
  • N. PilpelS. O. OTUYEMIT. Kurup
  • The Journal of pharmacy and pharmacology
  • 1978
  • Corpus ID: 21281895
A study has been made of the effects produced on the disintegration and dissolution times of chloroquine phosphate tablets by… 
1975
1975
Effect of compaction on particle size.
Compressed tablets were prepared on a hydraulic press at several different compaction pressures by a standardized technique… 
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