Diprenorphine

Known as: 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-, (5alpha,7alpha)-, Diprenorfin, Diprenorphine [Chemical/Ingredient] 
A narcotic antagonist similar in action to NALOXONE. It is used to remobilize animals after ETORPHINE neuroleptanalgesia and is considered a specific… (More)
National Institutes of Health

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10 relations

Narrower (2)

Diprenorphine HydrochlorideRevivon
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Broader (1)

Narcotic Antagonists

Papers overview

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2009
2009
Differential involvement of P-glycoprotein (ABCB1) in permeability, tissue distribution, and antinociceptive activity of methadone, buprenorphine, and diprenorphine: in vitro and in vivo evaluation.
Conclusions based on either in vitro or in vivo approach to evaluate the P-gp affinity status of opioids may be misleading. For… (More)
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Highly Cited
2004
Highly Cited
2004
Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [11C]diprenorphine PET study.
Based on concepts that endogenous opioids participate in neural transmission of pain, the present study in central poststroke… (More)
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2004
2004
Central poststroke pain and reduced opioid receptor binding within pain processing circuitries: a [<ce:sup loc=pre>11</ce:sup>C]diprenorphine PET study
Based on concepts that endogenous opioids participate in neural transmission of pain, the present study in central poststroke… (More)
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1999
1999
Measurement of changes in opioid receptor binding in vivo during trigeminal neuralgic pain using [11C] diprenorphine and positron emission tomography.
The binding of [11C]diprenorphine to mu, kappa, and delta subsites in cortical and subcortical structures was measured by… (More)
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1999
1999
Central pain after pontine infarction is associated with changes in opioid receptor binding: a PET study with 11C-diprenorphine.
Using 18F-fluorodeoxyglucose and 11C-diprenorphine positron emission tomography (PET), we investigated alterations in glucose… (More)
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Highly Cited
1994
Highly Cited
1994
Changes in central opioid receptor binding in relation to inflammation and pain in patients with rheumatoid arthritis.
A group of four patients with RA were examined to test the hypothesis that there is a change in the endogenous opioid system in… (More)
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Highly Cited
1982
Highly Cited
1982
The binding spectrum of narcotic analgesic drugs with different agonist and antagonist properties
Four groups of narcotic analgesic drugs have been assessed for their opiate activities by using three binding assays and three… (More)
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1982
1982
Effects of naloxone and diprenorphine on spontaneous activity in rats and mice
The narcotic antagonist naloxone has been reported to decrease locomotor activity in the rat, presumably blocking endogenous… (More)
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1981
1981
An autoradiographic map of (3H)diprenorphine binding in rat brain: effects of social interaction.
(3H)Diprenorphine binding was analyzed autoradiographically in the brains of 33 day old rat pups. A photographic atlas of… (More)
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Highly Cited
1977
Highly Cited
1977
Agonist and antagonist properties of buprenorphine, a new antinociceptive agent.
1. Buprenorphine is a highly lipophilic derivative of oripavine. In rodent antinociceptive assays (writhing, tail pressure… (More)
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