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Diphosphonates

Known as: bisphosphonate, biphosphonates, Diphosphonate 
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Bone metastases are a major burden in men with advanced prostate cancer. We compared denosumab, a human monoclonal… Expand
Review
2009
Review
2009
The 2009 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline on the management of chronic kidney… Expand
Review
2009
Review
2009
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) adversely affects the quality of life, producing significant morbidity in… Expand
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Review
2004
Review
2004
PURPOSE Bisphosphonates are widely used in the management of metastatic disease to the bone and in the treatment of osteoporosis… Expand
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Review
2001
Review
2001
  • R. Coleman
  • Cancer treatment reviews
  • 2001
  • Corpus ID: 41665983
Metastatic bone disease develops as a result of the many interactions between tumour cells and bone cells. This leads to… Expand
Highly Cited
1999
Highly Cited
1999
CONTEXT Risedronate, a potent bisphosphonate, has been shown to be effective in the treatment of Paget disease of bone and other… Expand
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Review
1994
Review
1994
Selective depletion of macrophages from tissues in vivo can be used to investigate whether these cells are playing a role in… Expand
Review
1981
Review
1981
  • M. Jarcho
  • Clinical orthopaedics and related research
  • 1981
  • Corpus ID: 205379256
Calcium Phosphate Ceramics as Hard Tissue Prosthetics MICHAEL JARCHO; Clinical Orthopaedics and Related Research 
Highly Cited
1969
Highly Cited
1969
Two diphosphonates containing the P-C-P bond, Cl2C(PO3HNa)2, and H2C(PO3HNa)2 retard the rate of dissolution of apatite crystals… Expand
Highly Cited
1969
Highly Cited
1969
Two diphosphonates containing the P-C-P bond, CH3C(OH)(PO3HNa)2 and H2C(PO3HNa)2, inhibit the crystallization of calcium… Expand