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Diphosphonates

Known as: bisphosphonate, biphosphonates, Diphosphonate 
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They… 
National Institutes of Health

Related topics

Related topics

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Narrower (38)

1-aminoethylene diphosphonic acid1-hydroxypentane-1,1-bisphosphonate2-iminopyrrolidone-5,5-diphosphonic acid99mTc-incadronate
5 ML zoledronic acid 0.8 MG/ML InjectionBisphosphonate [EPC]EtidronateEtidronate Disodium

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Bone health in cancer patients: ESMO Clinical Practice Guidelines.
There are three distinct areas of cancer management that make bone health in cancer patients of increasing clinical importance… 
Review
2014
Review
2014
Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial.
Review
2008
Review
2008
Low-Energy Femoral Shaft Fractures Associated With Alendronate Use
Objective: Increasing evidence suggests long-term alendronate use may overly suppress bone metabolism, limiting repair of… 
Highly Cited
2006
Highly Cited
2006
Confinement and controlled release of bisphosphonates on ordered mesoporous silica-based materials.
Bisphosphonates have been confined in siliceous ordered mesoporous materials, and the drug release rate of these systems has been… 
Highly Cited
2004
Highly Cited
2004
Osteoblast proliferation and maturation by bisphosphonates.
Highly Cited
1999
Highly Cited
1999
Risedronate therapy prevents corticosteroid-induced bone loss: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, parallel-group study.
OBJECTIVE Risedronate, a new pyridinyl bisphosphonate, is a potent antiresorptive bone agent. This study examines the safety and… 
Highly Cited
1998
Highly Cited
1998
Cyclic administration of pamidronate in children with severe osteogenesis imperfecta.
BACKGROUND Severe osteogenesis imperfecta is a disorder characterized by osteopenia, frequent fractures, progressive deformity… 
Highly Cited
1997
Highly Cited
1997
Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti‐tumour activity
Bisphosphonates are in widespread use to prevent bone resorption in a number of metabolic and tumour‐induced bone diseases… 
Review
1990
Review
1990
Glucocorticoid-induced osteoporosis: pathogenesis and management.
PURPOSE To review the clinical picture, pathogenesis, and management of glucocorticoid-induced osteoporosis. DATA… 
Highly Cited
1990
Highly Cited
1990
Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease.
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