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Diphosphonates

Known as: bisphosphonate, biphosphonates, Diphosphonate 
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They… 
National Institutes of Health

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1-aminoethylene diphosphonic acid1-hydroxypentane-1,1-bisphosphonate2-iminopyrrolidone-5,5-diphosphonic acid99mTc-incadronate
5 ML zoledronic acid 0.8 MG/ML InjectionBisphosphonate [EPC]EtidronateEtidronate Disodium

Papers overview

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2010
2010
More on the Resolution of Bisphosphonate-associated Osteonecrosis of the Jaw
To the Editor: We thank Drs. Duck-An Kim and Think-You Kim for their comments about our article1. We agree that hepatitis test… 
Highly Cited
2006
Highly Cited
2006
Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes.
Bisphosphonates are a class of molecules in widespread use in treating bone resorption diseases and are also of interest as… 
2006
2006
Investigation of the catalytic mechanism of farnesyl pyrophosphate synthase by computer simulation.
Farnesyl pyrophosphate synthase (FPPS) catalyses the formation of a key cellular intermediate in isoprenoid metabolic pathways… 
1997
1997
Bisphosphonate therapy : Management of osteoporosis, 1997
The bisphosphonates are long-lived synthetic analogs of pyrophosphate, a natural, short-lived inhibitor of bone. Oral doses share… 
1987
1987
gem-Diphosphonate and gem-phosphonate-phosphate compounds with specific high density lipoprotein inducing activity.
New diphosphonate compounds and related derivatives were synthesized and investigated for their activity in specifically inducing… 
1985
1985
Effect of bisphosphonates on prostaglandin synthesis by rat bone cells and mouse calvaria in culture.
Bisphosphonates are potent inhibitors of bone resorption and also inhibit prostaglandin (PG) E2 synthesis in bone cells… 
1985
1985
Bone resorption, metastasis, and diphosphonates
Inevitably, reading is one of the requirements to be undergone. To improve the performance and quality, someone needs to have… 
1981
1981
Parenteral diphosphonates for treating malignant hypercalcemia
Two diphosphonates, EHDP (disodium etidronate, or ethanehydroxy‐diphosphonate) and Cl2MDP (disodium clodronate, or… 
Highly Cited
1974
Highly Cited
1974
A proposed mechanism for 99mTc-labeled polyphosphate and diphosphonate uptake by human breast tissue.
Local uptake of 99mTc-polyphosphate or 99mTc-diphosphonate by breast tissue was observed in 17 patients, occurring in normal… 
Highly Cited
1971
Highly Cited
1971
Diphosphonate therapy in a patient with myositis ossificans progressiva.
Abstract A young man with severe debility from myositis ossificans progressiva was treated with sodium etidronate, a…