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Diphosphonates

Known as: bisphosphonate, biphosphonates, Diphosphonate 
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
OBJECTIVES The aim of Working Group 1 was to address the influence of different local (implant length, diameter, and design) and… Expand
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Review
2018
Review
2018
SummaryThe aim of this review was to identify factors that influence patients’ adherence to anti-osteoporotic therapy. Factors… Expand
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Review
2018
Review
2018
Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease… Expand
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Review
2017
Review
2017
BACKGROUND Bisphosphonates are specific inhibitors of osteoclastic activity and are used in the treatment of patients with… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Bone metastases are a major burden in men with advanced prostate cancer. We compared denosumab, a human monoclonal… Expand
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Highly Cited
2007
Highly Cited
2007
ONJ has been increasingly suspected to be a potential complication of bisphosphonate therapy in recent years. Thus, the ASBMR… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Bone metastases are a common cause of morbidity in patients with prostate carcinoma. We studied the effect of a new… Expand
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Highly Cited
1999
Highly Cited
1999
CONTEXT Risedronate, a potent bisphosphonate, has been shown to be effective in the treatment of Paget disease of bone and other… Expand
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Review
1997
Review
1997
The skeleton is the most common organ to be affected by metastatic cancer, and tumors arising from the breast, prostate, thyroid… Expand
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Highly Cited
1969
Highly Cited
1969
Two diphosphonates containing the P-C-P bond, Cl2C(PO3HNa)2, and H2C(PO3HNa)2 retard the rate of dissolution of apatite crystals… Expand
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