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Diphenoxylate

Known as: 2,2-Diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile, 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, Difenoxilato 
A piperidine derivate, chemically related to narcotic meperidine with antidiarrheal activity and devoid of central nervous system (CNS) activity… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Ulcerative colitis is a chronic inflammatory disease of the colon; as many as 25% of patients with this disease require… Expand
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Highly Cited
2011
Highly Cited
2011
The safe disposal of unused opioid drugs is an area of regulatory concern. While toilet flushing is recommended for some drugs to… Expand
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Highly Cited
2008
Highly Cited
2008
The objective of this study was to measure the anticholinergic activity (AA) of medications commonly used by older adults. A… Expand
Review
2003
Review
2003
BACKGROUND Faecal incontinence is a common symptom which causes significant distress and reduction in quality of life. Available… Expand
Highly Cited
2002
Highly Cited
2002
OBJECTIVE:There are no reports of the clinical features or treatment outcomes in large series of patients with lymphocytic… Expand
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Review
2001
Review
2001
PURPOSE: Fecal incontinence is a socially devastating disorder which affects at least 2.2 percent of community dwelling adults… Expand
Review
1997
Review
1997
  • R. Mcmillan
  • Annals of Internal Medicine
  • 1997
  • Corpus ID: 12018368
Adult chronic immune thrombocytopenic purpura (ITP) is an autoimmune disorder caused by one or more antiplatelet autoantibodies… Expand
Highly Cited
1984
Highly Cited
1984
The antidiarrheal opiates loperamide, fluperamide, diphenoxylate and fetoxylate inhibited binding of [3H]nitrendipine to… Expand
Highly Cited
1980
Highly Cited
1980
As no adequate comparison of these widely used drugs has been made, we have performed a double-blind cross-over trial in 30… Expand
Highly Cited
1973
Highly Cited
1973
IN a study comparing azathioprine and placebo in the management of patients with refractory granulomatous bowel disease, a… Expand