Diphenoxylate

Known as: 2,2-Diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile, 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, Difenoxilato 
A piperidine derivate, chemically related to narcotic meperidine with antidiarrheal activity and devoid of central nervous system (CNS) activity… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1961-2017
05101519612017

Papers overview

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Review
2013
Review
2013
BACKGROUND Lomotil (diphenoxylate atropine combination) has been in use as an antidiarrhoeal agent. Due to presence of opioid… (More)
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2011
2011
The safe disposal of unused opioid drugs is an area of regulatory concern. While toilet flushing is recommended for some drugs to… (More)
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Highly Cited
2008
Highly Cited
2008
The objective of this study was to measure the anticholinergic activity (AA) of medications commonly used by older adults. A… (More)
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2003
2003
This study examined the accumulation and transport of two related systemic opioids used as antidiarrhoeal drugs and compared… (More)
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1980
1980
As no adequate comparison of these widely used drugs has been made, we have performed a double-blind cross-over trial in 30… (More)
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1977
1977
Loperamide was compared double-blind with diphenoxylate and a placebo in 59 women with diarrhoea due to prostaglandin… (More)
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1976
1976
Loperamide, a novel antidiarrheal agent, was compared with diphenoxylate in a double blind crossover study of 23 patients with… (More)
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1976
1976
In this double-blind, randomized study, 200 normal subjects received a three-day course of one of five treatment regimens… (More)
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1975
1975
The mechanism of the gastrointestinal motility effects of diphenoxylate and morphine in preventing E prostaglandin (PG) diarrhea… (More)
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