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Dioxygenases

Known as: Dioxygenases [Chemical/Ingredient], dioxygenase 
Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS… Expand
National Institutes of Health

Related topics

Related topics

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Narrower (42)

1-hydroxy-2-naphthoate dioxygenase2,2',3-trihydroxybiphenyl dioxygenase2,3-dihydroxybiphenyl oxygenase2,4'-dihydroxyacetophenone dioxygenase
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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects
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Broader (1)

Oxygenases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins
As a result of the adaptation of life to an aerobic environment, nature has evolved a panoply of metalloproteins for oxidative… Expand
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Review
2017
Review
2017
Nitrate Reductase Regulates Plant Nitric Oxide Homeostasis.
Nitrate reductase (NR) is a key enzyme for nitrogen acquisition by plants, algae, yeasts, and fungi. Nitrate, its main substrate… Expand
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Review
2017
Review
2017
TET-mediated active DNA demethylation: mechanism, function and beyond
In mammals, DNA methylation in the form of 5-methylcytosine (5mC) can be actively reversed to unmodified cytosine (C) through TET… Expand
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Review
2017
Review
2017
TET family dioxygenases and DNA demethylation in stem cells and cancers
The methylation of cytosine and subsequent oxidation constitutes a fundamental epigenetic modification in mammalian genomes, and… Expand
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Review
2015
Review
2015
Plant betalains: Chemistry and biochemistry.
Betalains are vacuolar pigments composed of a nitrogenous core structure, betalamic acid [4-(2-oxoethylidene)-1,2,3,4… Expand
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Review
2013
Review
2013
Indoleamine 2,3 dioxygenase and metabolic control of immune responses.
Sustained access to nutrients is a fundamental biological need, especially for proliferating cells, and controlling nutrient… Expand
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Highly Cited
2011
Highly Cited
2011
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
IDH1 and IDH2 mutations occur frequently in gliomas and acute myeloid leukemia, leading to simultaneous loss and gain of… Expand
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Highly Cited
2011
Highly Cited
2011
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
Sperm and eggs carry distinctive epigenetic modifications that are adjusted by reprogramming after fertilization. The paternal… Expand
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Highly Cited
2005
Highly Cited
2005
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.
Indoleamine 2,3 dioxygenase (IDO) catabolizes the amino acid tryptophan. IDO-expressing immunoregulatory dendritic cells (DCs… Expand
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Highly Cited
2001
Highly Cited
2001
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. Recent studies have defined… Expand
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