Dimethindene

Known as: N,N-Dimethyl-3-(1-(2-Pyridinyl)Ethyl)-1H-Indene-2-Ethanamine, 2-(1-(2-(2-(Dimethylamino)Ethyl)Inden-3-yl)Ethyl)Pyridine, 3-(Alpha-(2'-Pyridyl)Ethyl)-2-(Beta-Dimethylaminoethyl)Indene 
A histamine H1 antagonist. It is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies.
National Institutes of Health

Papers overview

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2010
2010
BACKGROUND The basophil activation test (BAT) based on CD203c upregulation has been validated as a reliable tool for the… (More)
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2003
2003
BACKGROUND Loratadine is a second-generation histamine H(1)-receptor antagonist, used in the treatment of allergic conditions. No… (More)
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Highly Cited
1993
Highly Cited
1993
In superfused mouse striatal slices preincubated with [3H] dopamine 25 nmol/l, the electrically (3 Hz) evoked tritium overflow… (More)
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1993
1993
In pithed and vagotomized rats the effects of the H3 receptor agonist R-(−)-α-methylhistamine, the H1 receptor agonist 2-(2… (More)
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1992
1992
Mouse brain cortex slices preincubated with 3H-noradrenaline were superfused with physiological salt solution containing… (More)
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1991
1991
1. The effects of 10 mg (+)- and (-)-chlorpheniramine and 5 mg (+)- and (-)-dimethindene on daytime sleep latencies, digit symbol… (More)
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1991
1991
In pithed rats, the H3 agonist R-(-)-alpha-methylhistamine (R alpha MeHA) inhibited the electrically induced increase in blood… (More)
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1990
1990
Discs of pig retina were preincubated with 3H-noradrenaline, 3H-dopamine or 3H-serotonin and then superfused. Electrical field… (More)
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Highly Cited
1989
Highly Cited
1989
The effects of histamine and related drugs on the evoked tritium overflow from superfused rat brain cortex slices preincubated… (More)
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1974
1974
Histamine concentrations in canine whole blood and plasma were determined under several pharmacological, pathophysiological, and… (More)
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