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Dimethindene

Known as: N,N-Dimethyl-3-(1-(2-Pyridinyl)Ethyl)-1H-Indene-2-Ethanamine, 2-(1-(2-(2-(Dimethylamino)Ethyl)Inden-3-yl)Ethyl)Pyridine, 3-(Alpha-(2'-Pyridyl)Ethyl)-2-(Beta-Dimethylaminoethyl)Indene 
A histamine H1 antagonist. It is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The basophil activation test (BAT) based on CD203c upregulation has been validated as a reliable tool for the diagnosis of IgE… Expand
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Highly Cited
2009
Highly Cited
2009
Background:  The basophil activation test (BAT) is a widely validated and reliable tool especially for the diagnosis of… Expand
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Highly Cited
2005
Highly Cited
2005
In superfused mouse striatal slices preincubated with [3H] dopamine 25 nmol/l, the electrically (3 Hz) evoked tritium overflow… Expand
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Highly Cited
2004
Highly Cited
2004
SummaryThe effects of histamine and related drugs on the evoked tritium overflow from superfused rat brain cortex slices… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Loratadine is a second-generation histamine H(1)-receptor antagonist, used in the treatment of allergic conditions. No… Expand
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Highly Cited
1994
Highly Cited
1994
Although histamine release is recognised as a common event during anaesthesia and surgery, few clinicians judge the resultant… Expand
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1993
1993
SummaryIn pithed and vagotomized rats the effects of the H3 receptor agonist R-(−)-α-methylhistamine, the H1 receptor agonist 2… Expand
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Highly Cited
1992
Highly Cited
1992
SummaryMouse brain cortex slices preincubated with 3H-noradrenaline were superfused with physiological salt solution containing… Expand
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Highly Cited
1991
Highly Cited
1991
1 The effects of 10 mg (+)‐ and (−)‐chlorpheniramine and 5 mg (+)‐ and (−)‐dimethindene on daytime sleep latencies, digit symbol… Expand
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Highly Cited
1990
Highly Cited
1990
SummaryDiscs of pig retina were preincubated with 3H-noradrenaline, 3H-dopamine or 3H-serotonin and then superfused. Electrical… Expand
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