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Dimethindene

Known as: N,N-Dimethyl-3-(1-(2-Pyridinyl)Ethyl)-1H-Indene-2-Ethanamine, 2-(1-(2-(2-(Dimethylamino)Ethyl)Inden-3-yl)Ethyl)Pyridine, 3-(Alpha-(2'-Pyridyl)Ethyl)-2-(Beta-Dimethylaminoethyl)Indene 
A histamine H1 antagonist. It is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies.
National Institutes of Health

Related topics

Related topics

12 relations

Broader (3)

Anti-Allergic AgentsAntipruriticsHistamine H1 Antagonists

Narrower (2)

Dimethindene MaleateFenistil
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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1995
1995
Intraoperative Anaphylaxie auf Latex während der Schwangerschaft
ZusammenfassungBerichtet wird über einen intraoperativen anaphylaktischen Zwischenfall aufgrund einer gesicherten Latexallergie… 
1994
1994
Dimetindene versus astemizole in the treatment of itching eczematous disorders: a randomized, double-blind, comparative trial
We performed a randomized, double-blind, double-dummy trial to compare the antipruritic efficacy and tolerability of dimetindene… 
1993
1993
The use of cyclodextrin running buffers in capillary electrophoresis for enantioselective determination of the H-1 antihistaminic dimetindene in human urine
1992
1992
Studies on the effectiveness of H1-+H2-antagonist combinations in preventing life-threatening anaphylactoid reactions in anaesthesia and surgery: Problems with selecting the animal model from…
Animal models are necessary for studies on the effectiveness of histamine H1- + H2-receptor antagonists in preventing life… 
1986
1986
Electrophysiological characterization of histamine receptor subtypes in mammalian heart preparations
SummaryHistamine-induced electrophysiological effects have been investigated in guinea-pig left atria, papillary muscles and… 
Review
1985
Review
1985
H1 and H2 blockade: a prophylactic principle in anaesthesia and surgery against histamine-release responses of any degree of severity: Part II.
: In the perioperative period, histamine release was shown in numerous situations and pathological states. They include diseases… 
1971
1971
The effect of intraluminally administered drugs on implantation in normal pregnant rats.
It has been suggested that histamine released by an oestrogen surge at the time of implantation plays an important part in… 
1962
1962
Antipruritic potency of a new antihistamine dimethpyrindene: a comparative study with trimeprazine, a phenothiazine antihistamine.
1961
1961
Dimethpyrindene in pruritic and allergic skin disorders.
1960
1960
Preliminary experience with dimethpyrindene (forhistal), a new anthihistamine, in the treatment of seasonal allergic rhinitis.