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Introduction. This randomized, double-blind, placebo-controlled, ascending-dose study was conducted in healthy volunteers to… Expand We have investigated the time-course of the weal and flare inhibiting activity of dimethindene maleate in man and compared the… Expand The efficacy and tolerability of dimethindene maleate (CAS 3614-69-5, DMM, Fenistil) as drops in the treatment of pruritus in… Expand Twelve asymptomatic subjects (4 female, 8 male), being allergic to grass pollen proved by positive anamnesis, positive Prick-test… Expand The effects of dimethindene maleate (CAS 3614-69-5) on the central nervous system-as sustained release pellets (Fenistil OAD; OAD… Expand Capillary electrophoresis (CE) has been used for the chiral resolution of the basic racemic drug dimethindene (Fenistil) and its… Expand The aim of the study was to evaluate the efficacy and duration of two doses of dimethindene, in a sustained release pellet… Expand Dimethindene maleate (DM) (= Fenistil) is a potent antihistamine with a prolonged duration of action. On the histamine-stimulated… Expand The topical effect of the histamine H1-receptor antagonist dimethindene maleate on the wealing response to intradermal histamine… Expand Dimethpyrindene is intrinsically a potent, long lasting, orally effective antihistaminic, antiallergic drug. The specific… Expand