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Dihydrothymine

 
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
Repair of chemically modified bases in DNA is accomplished through base excision repair (BER). This pathway is initiated by a… Expand
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Highly Cited
2001
Highly Cited
2001
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5FU), and it… Expand
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Highly Cited
2000
Highly Cited
2000
Ionizing radiation and radiomimetic anticancer agents induce clustered DNA damage, which are thought to reflect the biological… Expand
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Highly Cited
1995
Highly Cited
1995
Energy deposition by ionizing radiation can lead to the formation of clustered DNA damage, i.e. more than one lesion situated… Expand
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Highly Cited
1994
Highly Cited
1994
Endonuclease VIII, a novel presumptive DNA repair enzyme, was isolated from Escherichia coli by FPLC1 purification. The enzyme… Expand
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Highly Cited
1993
Highly Cited
1993
We have used thymine glycol and dihydrothymine as representative ring saturation products resulting from free-radical interaction… Expand
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Highly Cited
1991
Highly Cited
1991
The processing of unrepaired DNA lesions is a key to understanding and predicting the biological end points of particular DNA… Expand
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Highly Cited
1984
Highly Cited
1984
In the urine of a child with unexplained convulsions large amounts of uracil and thymine were detected by gas chromatography… Expand
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Highly Cited
1981
Highly Cited
1981
Rat liver dihydrothymine dehydrogenase, the rate-limiting enzyme of thymidine and uridine degradation, was purified to… Expand
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1964
1964
TRITIATED thymidine is well recognised to be a highly specific precursor for DNA syntbesis in mammalian cells. During the past… Expand
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