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Dihydroorotate dehydrogenase

Known as: dihydro-orotate dehydrogenase 
National Institutes of Health

Related topics

Related topics

6 relations
DHODH geneDihydroorotate Oxidasedihydroorotate dehydrogenase activitydihydroorotate oxidase activity

Narrower (1)

Dihydroorotate Dehydrogenase (Quinone), Mitochondrial, human

Broader (1)

Oxidoreductases Acting on CH-CH Group Donors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Synthesis and in vitro evaluation of hydrazinyl phthalazines against malaria parasite, Plasmodium falciparum.
2013
2013
Babesia bovis Dihydroorotate Dehydrogenase (BboDHODH) is a Novel Molecular Target of Drug for Bovine Babesiosis
ABSTRACT The emergence of drug resistance and adverse side effects of current bovine babesiosis treatment suggest that the search… 
2011
2011
Substrate binding and reactivity are not linked: grafting a proton-transfer network into a Class 1A dihydroorotate dehydrogenase.
Adding the two residues comprising the conserved proton-transfer network of Class 2 dihydroorotate dehydrogenase (DHOD) to the… 
2010
2010
Immunopathology and Infectious Diseases 4 SC-101 , A Novel Small Molecule Dihydroorotate Dehydrogenase Inhibitor , Suppresses Systemic Lupus Erythematosus in MRL-( Fas ) lpr Mice
Immunosuppressive treatments of systemic lupus (SLE) remain associated with significant toxicities; hence, compounds with better… 
2005
2005
Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate.
Dihydroorotate dehydrogenase (DHOD) catalyzes the oxidation of dihydroorotate to orotate, the fourth step and the only redox… 
2004
2004
Multiple states of the Tyr318Leu mutant of dihydroorotate dehydrogenase revealed by single-molecule kinetics.
Dihydroorotate dehydrogenase (DHOD) from Escherichia coli is a monomeric membrane-associated flavoprotein that catalyzes the… 
2003
2003
Dihydroorotate dehydrogenase of Escherichia coli.
Dihydroorotate dehydrogenase (DHOD) catalyzes the fourth reaction in the pathway for de novo synthesis of UMP and forms the 5,6… 
1999
1999
MALONONITRILAMIDES (MNAs) EXERT THEIR IMMUNOSUPPRESSIVE ACTIVITY PRIMARILY BY INHIBITION OF DIHYDROOROTATE DEHYDROGENASE (DHODH).
1999
1999
Expression and characterization of E. coli-produced soluble, functional human dihydroorotate dehydrogenase: a potential target for immunosuppression.
Human dihydroorotate dehydrogenase (huDHODH) is essential for de novo biosynthesis of pyrimidines and the target of two… 
1991
1991
Purification and characterization of dihydroorotate dehydrogenase from the rodent malaria parasite Plasmodium berghei.
Dihydroorotate dehydrogenase (DHODase) has been purified 400-fold from the rodent malaria parasite Plasmodium berghei to apparent… 
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