Skip to search formSkip to main contentSkip to account menu

DHODH gene

Known as: dihydroorotate dehydrogenase (quinone), Dihydroorotate Dehydrogenase Gene, DHOdehase 
This gene plays a role in pyrimidine metabolism.
National Institutes of Health

Related topics

Related topics

5 relations
AnabolismDihydroorotate Dehydrogenase (Quinone), Mitochondrial, humanDihydroorotate dehydrogenaseNucleotide Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Precision Medicine With Leflunomide: Consideration of the DHODH Haplotype and Plasma Teriflunomide Concentration and Modification of Outcomes in Patients With Rheumatoid Arthritis
Leflunomide is a commonly used disease‐modifying drug in the treatment of rheumatoid arthritis (RA). Its effects are mediated via… 
2017
2017
Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition
Reduction in nucleotide pools through the inhibition of mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) has been… 
2017
2017
PTC299 Is a Novel DHODH Inhibitor That Modulates VEGFA mRNA Translation and Inhibits Proliferation of a Broad Range of Leukemia Cells
PTC299 was identified in a phenotypic high through put screen as an inhibitor of VEGFA mRNA translation and had been in clinical… 
2006
2006
Biphenyl-4-ylcarbamoyl thiophene carboxylic acids as potent DHODH inhibitors.
2004
2004
Discovery of a novel series of DHODH inhibitors by a docking procedure and QSAR refinement.
1995
1995
Expression of the dihydroorotate dehydrogenase gene, dhod, during spermatogenesis in Drosophila melanogaster
The dhod gene encodes dihydroorotate dehydrogenase (DHOdehase), which catalyzes the fourth step of de novo pyrimidine… 
1994
1994
Molecular cloning and sequence analyses of rat liver dihydroorotate dehydrogenase.
Dihydroorotate dehydrogenase (DHOdehase) catalyzes the fourth step of de novo pyrimidine synthesis, the conversion of… 
1993
1993
The dhod gene and deduced structure of mitochondrial dihydroorotate dehydrogenase in Drosophila melanogaster.
We have carried out experiments to determine the structural organization of dhod and its apparent dihydroorotate dehydrogenase… 
1992
1992
Sequence of the URA1 gene encoding dihydroorotate dehydrogenase from the basidiomycete fungus Agrocybe aegerita.
1969
1969
Pyrimidine Synthesis in Neurospora crassa: Regulation of Enzyme Activities
The regulation of several enzymes involved in pyrimidine biosynthesis in Neurospora crassa has been studied. Elevation of ATCase… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)