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Dihydroergotamine

Known as: (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraene-4-carboxamide, 9,10-dihydroergotamine, Dihydroergotamin 
A 9,10alpha-dihydro derivative of ERGOTAMINE. It is used as a vasoconstrictor, specifically for the therapy of MIGRAINE DISORDERS.
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (16)

8'-hydroxydihydroergotamineClavigreninDHE-45DHE-Puren
Adrenergic alpha-Antagonists [MoA]AmprenavirAngina Pectoris, VariantCluster Headache

Broader (4)

AnalgesicsAnalgesics, Non-NarcoticDopamine AgonistsVasoconstrictor Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system
Review
2000
Review
2000
Amprenavir: a new human immunodeficiency virus type 1 protease inhibitor.
Highly Cited
1989
Highly Cited
1989
Excitatory and inhibitory effects of epinephrine on neonatal rat sympathetic preganglionic neurons in vitro
1987
1987
Noradrenaline-induced emesis Alpha-2 adrenoceptor mediation in the area postrema
Highly Cited
1985
Highly Cited
1985
Depletion of neuropeptides in rat parotid glands and declining atropine-resistant salivary secretion upon continuous parasympathetic nerve stimulation
1982
1982
High-affinity octopamine receptors revealed in Drosophila by binding of [3H]octopamine
Highly Cited
1977
Highly Cited
1977
A comparison of pre- and postsynaptic effects of α-adrenolytic drugs in the pulmonary artery of the rabbit
Highly Cited
1976
Highly Cited
1976
EFFICACY OF LOW-DOSE HEPARIN IN PREVENTION OF EXTENSIVE DEEP-VEIN THROMBOSIS IN PATIENTS UNDERGOING TOTAL-HIP REPLACEMENT
Highly Cited
1973
Highly Cited
1973
Lack of correlation between catecholamine effects on cyclic adenosine 3':5'-monophosphate and gluconeogenesis in isolated rat liver cells.
Highly Cited
1971
Highly Cited
1971
Hormone action at the membrane level. 3. Epinephrine interaction with the rat liver plasma membrane.
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