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Brain stem activation in spontaneous human migraine attacks
TLDR
Findings support the idea that the pathogenesis of migraine is related to an imbalance in activity between brain stem nuclei regulating antinociception and vascular control. Expand
Medication-overuse headache: a worldwide problem
TLDR
The new international classification of headache disorders has now incorporated additional criteria and new headache entities that will facilitate the diagnosis of MOH. Expand
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
TLDR
The anti-inflammatory effects and favourable safety profile of BG00012 warrant further long-term phase III studies in large patient groups. Expand
Guidelines for Controlled Trials of Prophylactic Treatment of Chronic Migraine in Adults
TLDR
These Guidelines are intended to assist in the design of well-controlled clinical trials of chronic migraine in adults, and do not apply to studies in children or adolescents. Expand
A Novel Method of Eliciting Pain‐Related Potentials by Transcutaneous Electrical Stimulation
TLDR
This work has proposed a novel technique of noninvasive transcutaneous electrical stimulation of trigeminal and somatic pain transmission in humans using laser and contact heat evoked pain‐related potentials. Expand
Medication Overuse Headache: Rates and Predictors for Relapse in a 4-year Prospective Study
TLDR
The study suggests that the majority of relapses occur within the first year after withdrawal and that the long-term success of withdrawal depends on the type of primary headache and thetype of overused medication. Expand
Costs and quality of life of multiple sclerosis in Germany
TLDR
This cost-of-illness analysis based on information from 2973 patients with multiple sclerosis (MS) in Germany is part of a Europe-wide study on the costs and quality of life related to the level of disease severity. Expand
Features of medication overuse headache following overuse of different acute headache drugs
TLDR
Although patients overusing ergots and analgesics typically had a daily tension-type headache, patients with triptan-induced MOH were more likely to describe a (daily) migrainelike headache or an increase in migraine frequency. Expand
Prevalence of migraine, tension‐type headache and trigeminal neuralgia in multiple sclerosis
TLDR
This study aimed to investigate the 1 year prevalence of headache in MS compared with the general population and found no significant differences between patients with and without multiple sclerosis. Expand
The NOS Inhibitor, 7-Nitroindazole, Decreases Focal Infarct Volume but Not the Response to Topical Acetylcholine in Pial Vessels
TLDR
If the effects of 7-NI are mediated by inhibition of nNOS activity, these results suggest that enzymatic products of the neuronal isoform promote ischemic injury and that they do so at least within the first few hours after permanent occlusion. Expand
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