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XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors.
Based on structural and evolutionary criteria, neuropeptide Y (NPY)b, peptide YY (PYY) and pancreatic polypetide (PP) are closely related polypeptides ([Larhammar, 1996a][1]). They are composed of 36Expand
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Adrenergic and muscarinic receptors in the human heart.
Cardiac function is controlled by the autonomic nervous system (i.e., the sympathetic and the parasympathetic nervous systems), which act via adrenoceptors and muscarinic acetylcholine receptors,Expand
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Alpha1-, alpha2- and beta-adrenoceptors in the urinary bladder, urethra and prostate.
1 We have systematically reviewed the presence, functional responses and regulation of alpha(1)-, alpha(2)- and beta-adrenoceptors in the bladder, urethra and prostate, with special emphasis on humanExpand
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Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptor.
To investigate the functional role of different alpha1-adrenergic receptor (alpha1-AR) subtypes in vivo, we have applied a gene targeting approach to create a mouse model lacking the alpha1b-ARExpand
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α1‐, α2‐ and β‐adrenoceptors in the urinary bladder, urethra and prostate
We have systematically reviewed the presence, functional responses and regulation of α1‐, α2‐ and β‐adrenoceptors in the bladder, urethra and prostate, with special emphasis on human tissues andExpand
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Pharmacological treatment of overactive bladder: report from the International Consultation on Incontinence
Purpose of review Treatment options for the overactive bladder were recently discussed at the 4th International Consultation on Incontinence (ICI) held in Paris, 5–8 July 2008. This article willExpand
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Cardiovascular effects of sphingosine‐1‐phosphate and other sphingomyelin metabolites
Upon various stimuli, cells metabolize sphingomyelin from the cellular plasma membrane to form sphingosylphosphorylcholine (SPC) or ceramide. The latter can be further metabolized to sphingosine andExpand
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The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy.
alpha 1-Adrenergic agonists induce a hypertrophic phenotype in cultured neonatal rat ventricular myocytes. Quantifiable markers of this phenotype include stimulation of phosphoinositide hydrolysis,Expand
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Effect of diabetes on lower urinary tract symptoms in patients with benign prostatic hyperplasia.
PURPOSE Several studies have suggested a specific association between the presence and/or symptom intensity of benign prostatic hyperplasia (BPH) and diabetes but to our knowledge no definitiveExpand
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Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets.
By virtue of their large number, widespread distribution and important roles in cell physiology and biochemistry, G-protein-coupled receptors (GPCR) play multiple important roles in clinicalExpand
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