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Diazoxide

Known as: Diazoxide [Chemical/Ingredient], 3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-Dioxide, 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide 
A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Reactive oxygen species (ROS) are key mediators in signal transduction of angiotensin II (Ang II). However, roles of vascular… Expand
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Highly Cited
2001
Highly Cited
2001
Diazoxide, a selective opener of the mitochondrial ATP-sensitive potassium channel, has been shown to elicit tolerance to… Expand
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Review
2000
Review
2000
Glucose stimulates insulin secretion by generating triggering and amplifying signals in beta-cells. The triggering pathway is… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Brief interruptions of coronary blood flow paradoxically protect the heart from subsequent prolonged ischemia. The… Expand
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Highly Cited
1997
Highly Cited
1997
Previous studies showed a poor correlation between sarcolemmal K+ currents and cardioprotection for ATP-sensitive K+ channel… Expand
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Highly Cited
1997
Highly Cited
1997
ATP-sensitive potassium channels (K-ATP channels) couple cell metabolism to electrical activity and are important in the… Expand
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Highly Cited
1996
Highly Cited
1996
We have cloned an isoform of the sulfonylurea receptor (SUR), designated SUR2. Coexpression of SUR2 and the inward rectifier K… Expand
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Highly Cited
1995
Highly Cited
1995
A member of the inwardly rectifying potassium channel family was cloned here. The channel, called BIR (Kir6.2), was expressed in… Expand
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Highly Cited
1989
Highly Cited
1989
Vasodilators are used clinically for the treatment of hypertension and heart failure. The effects of some vasodilators seem to be… Expand
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Highly Cited
1989
Highly Cited
1989
To test the hypothesis that insulin plays a role in the hyperandrogenism of obese women with polycystic ovary syndrome, we… Expand
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