Dexmedetomidine Hydrochloride

Known as: DEXMEDETOMIDINE HCL, Dexmedetomidine Hydrochloride [Chemical/Ingredient], Hydrochloride, Dexmedetomidine 
The hydrochloride salt form of dexmedetomidine, an imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic and sedative… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
0102019802018

Papers overview

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2013
2013
BACKGROUND Dexmedetomidine is an α-2-receptor agonist which might be used as an additive to local anaesthetics for various… (More)
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2009
2009
BACKGROUND The current study was designed to test the hypothesis that dexmedetomidine added to ropivacaine would increase the… (More)
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2009
2009
BACKGROUND Subarachnoid hemorrhage is a serious condition, often accompanied by cerebral vasospasm, which may lead to brain… (More)
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Highly Cited
2004
Highly Cited
2004
UNLABELLED Thirty-four patients scheduled for elective inpatient surgery were randomized equally to receive either… (More)
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Highly Cited
2002
Highly Cited
2002
UNLABELLED Dexmedetomidine is a selective alpha(2)-agonist approved for sedation of critically ill patients. There is little… (More)
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Highly Cited
2000
Highly Cited
2000
The clinical effects and pharmacokinetics of medetomidine (MED) and its enanti-omers, dexmedetomidine (DEX) and levomedetomidine… (More)
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1998
1998
Alpha-2 adrenergic receptors (alpha2 AR) mediate incorporation of guanosine 5'-O-(gamma-thio)triphosphate ([35S]GTPgammaS) into… (More)
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Highly Cited
1997
Highly Cited
1997
UNLABELLED Dexmedetomidine is a selective alpha2-adrenoceptor agonist with centrally mediated sympatholytic, sedative, and… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Dexmedetomidine is an alpha 2 agonist with potential utility in clinical anesthesia for both its sedative and… (More)
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1993
1993
BACKGROUND This investigation extended the pharmacokinetic analysis of our previous study, of intravenous dexmedetomidine in 10… (More)
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