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Dexmedetomidine Hydrochloride

Known as: DEXMEDETOMIDINE HCL, Dexmedetomidine Hydrochloride [Chemical/Ingredient], Hydrochloride, Dexmedetomidine 
The hydrochloride salt form of dexmedetomidine, an imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic and sedative… 
National Institutes of Health

Related topics

Related topics

11 relations
2 ML Dexmedetomidine 0.1 MG/ML Injection2 ML Dexmedetomidine 0.1 MG/ML Injection [Precedex]Adrenergic alpha1-Agonists [MoA]Adrenergic alpha2-Agonists [MoA]

Narrower (2)

DexdomitorPrecedex

Broader (1)

Dexmedetomidine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Dexmedetomidine ameliorates LPS induced acute lung injury via GSK-3β/STAT3-NF-κB signaling pathway in rats.
Review
2014
Review
2014
Pharmacological treatments of non-substance-withdrawal delirium: a systematic review of prospective trials.
OBJECTIVE Most reviews of pharmacological strategies for delirium treatment evaluate the effectiveness of these interventions for… 
Highly Cited
2011
Highly Cited
2011
Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-activated Cation Current
Background: The current study was designed to test the hypothesis that the increased duration of analgesia caused by adding… 
Highly Cited
2010
Highly Cited
2010
Perineural Dexmedetomidine Provides an Increased Duration of Analgesia to a Thermal Stimulus When Compared With a Systemic Control in a Rat Sciatic Nerve Block
Background and Objectives: The present study was designed to test the hypothesis that perineural dexmedetomidine provides a… 
Highly Cited
2009
Highly Cited
2009
Perineural Dexmedetomidine Added to Ropivacaine Causes a Dose-dependent Increase in the Duration of Thermal Antinociception in Sciatic Nerve Block in Rat
Background:The current study was designed to test the hypothesis that dexmedetomidine added to ropivacaine would increase the… 
Highly Cited
2009
Highly Cited
2009
Effect of Dexmedetomidine on Ischemia-Reperfusion Injury in Rat Kidney: A Histopathologic Study
Ischemia-reperfusion (I-R) injury remains the leading cause of acute renal failure. The purpose of this experimental study was to… 
Highly Cited
2000
Highly Cited
2000
Effects of Radolmidine, A Novel &agr;2-Adrenergic Agonist Compared with Dexmedetomidine in Different Pain Models in the Rat
Background Intrathecally administered &agr;2-adrenoceptor agonists produce effective antinociception, but sedation is an… 
Highly Cited
1994
Highly Cited
1994
Spinal and Systemic Action of the α2 Receptor Agonist Dexmedetomidine in Dogs: Antinociception and Carbon Dioxide Response
Background:4aL2 Agonists are powerful analgesics after spinal delivery. The current work characterizes the dose-dependent… 
Highly Cited
1994
Highly Cited
1994
Dexmedetomidine premedication before intravenous regional anesthesia in minor outpatient hand surgery.
Highly Cited
1990
Highly Cited
1990
Dexmedetomidine Premedication for Minor Gynecologic Surgery
The effects of four different doses (0.167, 0.33, 0.67, and 1.0 μg/kg) of dexmedetomidine, a novel α2-adrenoceptor agonist, on… 
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