Skip to search formSkip to main contentSkip to account menu

Dexmedetomidine

Known as: 1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-, (R)-, Dexmedetomidin, Dexmédétomidine 
An imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic and sedative properties. Dexmedetomidine selectively binds to… 
National Institutes of Health

Related topics

Related topics

25 relations
2 ML Dexmedetomidine 0.1 MG/ML Injection2 ML Dexmedetomidine 0.1 MG/ML Injection [Precedex]Adrenergic alpha1-Agonists [MoA]Adrenergic alpha2-Agonists [MoA]

Broader (3)

Adrenergic alpha-2 Receptor AgonistsAnalgesics, Non-NarcoticHypnotics and Sedatives

Narrower (5)

DexdomitorDexmedetomidine HydrochlorideMPV-1440Precedex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The effect of dexmedetomidine on expressions of inflammatory factors in patients with radical resection of gastric cancer.
OBJECTIVE To investigate the effect of dexmedetomidine on the expressions of inflammatory factors, T-lymphocyte subgroups and… 
Highly Cited
2014
Highly Cited
2014
Systemic dexmedetomidine augments inhibitory synaptic transmission in the superficial dorsal horn through activation of descending noradrenergic control: An in vivo patch-clamp analysis of analgesic…
α 2 -adrenoceptors are widely distributed throughout the central nervous system (CNS) and the systemic administration of α 2… 
2011
2011
Modulation of postjunctional α‐adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans
Non‐technical summary  When muscles contract, a variety of signals interact and ultimately increase blood flow and oxygen… 
Highly Cited
2011
Highly Cited
2011
High-Dose Dexmedetomidine for Sedation in the Intensive Care Unit: An Evaluation of Clinical Efficacy and Safety
BACKGROUND: Dexmedetomidine is an α2-receptor agonist used for sedation in the intensive care unit (ICU). Although… 
Highly Cited
2009
Highly Cited
2009
The Effects of Dexmedetomidine and Fentanyl on Emergence Characteristics after Adenoidectomy in Children
This randomised controlled study evaluated the effects of fentanyl and dexmedetomidine on emergence characteristics of children… 
2006
2006
Dexmedetomidine infusion is associated with enhanced renal function after thoracic surgery.
STUDY OBJECTIVE To test the hypothesis that dexmedetomidine, a selective alpha-2 agonist, enhances urine flow rate and… 
Highly Cited
2005
Highly Cited
2005
Rescue sedation with dexmedetomidine for diagnostic imaging: a preliminary report
Background : Sedation is frequently required during noninvasive radiological imaging in children. Although commonly used agents… 
Highly Cited
2001
Highly Cited
2001
Effects of dexmedetomidine after transient and permanent occlusion of the middle cerebral artery in the rat
Summary. Increased sympathetic tone is a consequence of cerebral ischemia. Although the role of catecholamines in ischemic damage… 
1999
1999
Drug release from a porous ion-exchange membrane in vitro.
Highly Cited
1974
Highly Cited
1974
INFECTIOUS AGAMMAGLOBULINEMIA: TRANSMISSION OF IMMUNODEFICIENCY WITH GRAFTS OF AGAMMAGLOBULINEMIC CELLS
Agammaglobulinemia induced in chickens by surgical bursectomy and irradiation at hatching is transmissible at 4 mo of age to… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)