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Desmosine

Known as: 4-[(4S)-4-Amino-4-Carboxybutyl]-1-[(5S)-5-Amino-5-Carboxypentyl]-3,5-Bis[(3S)-3-Amino-3-Carboxypropyl]Pyridinium, 6-{4-[(4S)-4-Amino-4-Carboxybutyl]-3,5-Bis[(3S)-3-Amino-3-Carboxypropyl]-1-Pyridiniumyl}-L-Norleucine, Desmosine [Chemical/Ingredient] 
An amino acid derivative comprised of three allysyl side chains plus one unaltered lysyl side chain from the same or neighboring polypeptides… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Oxidative stress is central to neuronal damage in neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease… Expand
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Highly Cited
2004
Highly Cited
2004
SummaryThe fast potentiometric indicator di-4-ANEPPS is examined in four different preparations: lipid vesicles, red blood cells… Expand
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Highly Cited
2003
Highly Cited
2003
The autofluorescent pigments that accumulate in retinal pigment epithelial cells with aging and in some retinal disorders have… Expand
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Highly Cited
2003
Highly Cited
2003
We have identified ghrelin from the stomach of rainbow trout. Four isoforms of ghrelin peptide were isolated: the C-terminal… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE When the pyridinium bisretinoid A2E, an age-related fluorophore in the retinal pigment epithelium (RPE), is irradiated… Expand
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Highly Cited
2001
Highly Cited
2001
Due to the structural similarity to N-methyl-4-phenyl pyridinium (MPP(+)), paraquat might induce dopaminergic toxicity in the… Expand
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Highly Cited
2000
Highly Cited
2000
The autofluorescent lipofuscin that accumulates in retinal pigment epithelial cells with age may contribute to an age-related… Expand
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Highly Cited
1997
Highly Cited
1997
A high-performance liquid chromatographic assay was developed for pyridinium crosslinks and pentosidine in mature collagen of a… Expand
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Highly Cited
1996
Highly Cited
1996
which no remedy exists. It is generally accepted that the pigments are formed as a consequence of accumulation of debris… Expand
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Highly Cited
1991
Highly Cited
1991
INTAKE of MPTP (l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine) leads to symptoms of Parkinson's disease and produces degeneration… Expand
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