FAQ

Desmocollins

Known as: Desmocollins [Chemical/Ingredient], desmocollin 
A group of desmosomal cadherins with cytoplasmic tails that are divergent from those of classical CADHERINS. Their intracytoplasmic domains bind… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2017
0102019842017

Related topics

Related topics

11 relations
CadherinsIn BloodProcess of secretionadministration & dosage
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Desmocollins
physiological aspects
agonists
Cadherins
chemical synthesis
standards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Autoantibodies against desmocollins in European patients with pemphigus.
BACKGROUND Autoimmune bullous disorders of the pemphigus group are characterized by autoantibodies targeting desmoglein (Dsg)1… (More)
Is this relevant?
2008
2008
Loss of desmocollin 3 in mice leads to epidermal blistering.
Desmocollin 3 (DSC3) belongs to a subfamily of cadherins and is a major component of desmosomes in keratinocytes of stratified… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis.
IL-22 is an IFN-IL-10 cytokine family member, which is produced by activated Th1 and NK cells and acts primarily on epithelial… (More)
Is this relevant?
2004
2004
Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion.
Desmoglein 1 (Dsg1) is a component of desmosomes present in the upper epidermis and can be targeted by autoimmune antibodies or… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation
The desmosomal cadherin desmocollin (Dsc)1 is expressed in upper epidermis where strong adhesion is required. To investigate its… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1996
1996
Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells.
Murine monoclonal antibodies (mAbs) which specifically react, in immunoblot and immunolocalization experiments, with the human… (More)
Is this relevant?
1995
1995
The widespread human desmocollin Dsc2 and tissue-specific patterns of synthesis of various desmocollin subtypes.
By comparison of the cDNA-derived amino acid sequences and the cell type-specific patterns of synthesis we have identified… (More)
Is this relevant?
1994
1994
Identification of amino acid sequence motifs in desmocollin, a desmosomal glycoprotein, that are required for plakoglobin binding and plaque formation.
By transfecting epithelial cells with gene constructs encoding chimeric proteins of the transmembrane part of the gap junction… (More)
Is this relevant?
1991
1991
Desmocollins form a distinct subset of the cadherin family of cell adhesion molecules.
The desmosomal adhesive core is formed by four major components: desmoglein (Mr, 165,000), desmocollins I and II (Mr, 120,000 and… (More)
  • figure 1
  • table 1
  • figure 3
Is this relevant?
1984
1984
Identification of desmosomal surface components (desmocollins) and inhibition of desmosome formation by specific Fab'.
Specific antibodies against the components of desmosomes, the adhesive junctions of epithelial cells, have been used to determine… (More)
Is this relevant?