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Denaturing Gradient Gel Electrophoresis
Known as:
DGGE
Electrophoresis in which various denaturant gradients are used to induce nucleic acids to melt at various stages resulting in separation of molecules…
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National Institutes of Health
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Related topics
Related topics
5 relations
Base Sequence
Temperature Gradient Gel Electrophoresis
standards characteristics
Broader (2)
Gel Electrophoresis (lab technique)
Genetic Techniques
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Monitoring the lactic acid bacterial diversity during shochu fermentation by PCR-denaturing gradient gel electrophoresis.
A. Endo
,
S. Okada
Journal of Bioscience and Bioengineering
2005
Corpus ID: 22367636
The presence of lactic acid bacteria (LAB) during shochu fermentation was monitored by PCR-denaturing gradient gel…
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Highly Cited
2002
Highly Cited
2002
Microbial community changes during organic solid waste treatment analyzed by double gradient-denaturing gradient gel electrophoresis and fluorescence in situ hybridization
Haruta S.
,
Kondo M.
,
+4 authors
Igarashi Y.
Applied Microbiology and Biotechnology
2002
Corpus ID: 13275867
Abstract. The bacterial community present during semicontinuous treatment of organic solid waste under alkaline and high…
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Highly Cited
1999
Highly Cited
1999
Spatial and Temporal Assessment of Diazotroph Assemblage Composition in Vegetated Salt Marsh Sediments Using Denaturing Gradient Gel Electrophoresis Analysis
Y. Piceno
,
P. Noble
,
C. R. Lovell
Microbial Ecology
1999
Corpus ID: 17611966
A bstractDiazotroph assemblage compositions were assessed in rhizosphere sediments from the tall and short form Spartina…
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Highly Cited
1999
Highly Cited
1999
Improvements in gel composition and electrophoretic conditions for broad-range mutation analysis by denaturing gradient gel electrophoresis.
V. Hayes
,
Ying Wu
,
+5 authors
R. Hofstra
Nucleic Acids Research
1999
Corpus ID: 8144576
Denaturing gradient gel electrophoresis (DGGE) is believed to be the most powerful pre-screening method for mutation detection…
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Highly Cited
1994
Highly Cited
1994
Relative efficiency of denaturing gradient gel electrophoresis and single strand conformation polymorphism in the detection of mutations in exons 5 to 8 of the p53 gene.
C. Moyret
,
C. Theillet
,
P. Puig
,
J. Molès
,
G. Thomas
,
R. Hamelin
Oncogene
1994
Corpus ID: 27800677
p53 is the most commonly mutated gene in a large variety of human tumors including familial cancers. Because p53 mutations have…
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Highly Cited
1993
Highly Cited
1993
Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors.
Richard Hamelin
,
N. Jego
,
Pierre Laurent-Puig
,
M. Vidaud
,
Gareth J. Thomas
Oncogene
1993
Corpus ID: 23475584
Alterations in exons 5-8 of the p53 gene have been found in the vast majority of human tumors. Although some specific codons have…
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Highly Cited
1991
Highly Cited
1991
Identification of novel rhodopsin mutations associated with retinitis pigmentosa by GC-clamped denaturing gradient gel electrophoresis.
V. C. Sheffield
,
Gerald A. Fishman
,
John S. Beck
,
Alan E. Kimura
,
E. Stone
American Journal of Human Genetics
1991
Corpus ID: 25392659
Retinitis pigmentosa (RP) is a group of disorders characterized by progressive degeneration of the outer retina, resulting in…
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Highly Cited
1990
Highly Cited
1990
Mutations and a polymorphism in the factor VIII gene discovered by denaturing gradient gel electrophoresis.
S. Kogan
,
J. Gitschier
Proceedings of the National Academy of Sciences…
1990
Corpus ID: 9391764
Hemophilia A results from mutations in the gene coding for coagulation factor VIII. We used denaturing gradient gel…
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Highly Cited
1990
Highly Cited
1990
Identification of the multiple beta-thalassemia mutations by denaturing gradient gel electrophoresis.
S. Cai
,
Y. Kan
Journal of Clinical Investigation
1990
Corpus ID: 31562734
We used denaturing gradient gel electrophoresis to detect the beta-thalassemia mutations in the Chinese population. By amplifying…
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Highly Cited
1985
Highly Cited
1985
Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis.
R. Myers
,
S. Fischer
,
T. Maniatis
,
L. Lerman
Nucleic Acids Research
1985
Corpus ID: 15756568
The melting behavior of a DNA fragment carrying the mouse beta maj-globin promoter was investigated as a means of establishing…
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