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Denaturing Gradient Gel Electrophoresis

Known as: DGGE 
Electrophoresis in which various denaturant gradients are used to induce nucleic acids to melt at various stages resulting in separation of molecules… 
National Institutes of Health

Related topics

Related topics

5 relations
Base SequenceTemperature Gradient Gel Electrophoresisstandards characteristics

Broader (2)

Gel Electrophoresis (lab technique)Genetic Techniques

Papers overview

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Highly Cited
2005
Highly Cited
2005
Monitoring the lactic acid bacterial diversity during shochu fermentation by PCR-denaturing gradient gel electrophoresis.
The presence of lactic acid bacteria (LAB) during shochu fermentation was monitored by PCR-denaturing gradient gel… 
Highly Cited
2002
Highly Cited
2002
Microbial community changes during organic solid waste treatment analyzed by double gradient-denaturing gradient gel electrophoresis and fluorescence in situ hybridization
Abstract. The bacterial community present during semicontinuous treatment of organic solid waste under alkaline and high… 
Highly Cited
1999
Highly Cited
1999
Spatial and Temporal Assessment of Diazotroph Assemblage Composition in Vegetated Salt Marsh Sediments Using Denaturing Gradient Gel Electrophoresis Analysis
A bstractDiazotroph assemblage compositions were assessed in rhizosphere sediments from the tall and short form Spartina… 
Highly Cited
1999
Highly Cited
1999
Improvements in gel composition and electrophoretic conditions for broad-range mutation analysis by denaturing gradient gel electrophoresis.
Denaturing gradient gel electrophoresis (DGGE) is believed to be the most powerful pre-screening method for mutation detection… 
Highly Cited
1994
Highly Cited
1994
Relative efficiency of denaturing gradient gel electrophoresis and single strand conformation polymorphism in the detection of mutations in exons 5 to 8 of the p53 gene.
p53 is the most commonly mutated gene in a large variety of human tumors including familial cancers. Because p53 mutations have… 
Highly Cited
1993
Highly Cited
1993
Efficient screening of p53 mutations by denaturing gradient gel electrophoresis in colorectal tumors.
Alterations in exons 5-8 of the p53 gene have been found in the vast majority of human tumors. Although some specific codons have… 
Highly Cited
1991
Highly Cited
1991
Identification of novel rhodopsin mutations associated with retinitis pigmentosa by GC-clamped denaturing gradient gel electrophoresis.
Retinitis pigmentosa (RP) is a group of disorders characterized by progressive degeneration of the outer retina, resulting in… 
Highly Cited
1990
Highly Cited
1990
Mutations and a polymorphism in the factor VIII gene discovered by denaturing gradient gel electrophoresis.
Hemophilia A results from mutations in the gene coding for coagulation factor VIII. We used denaturing gradient gel… 
Highly Cited
1990
Highly Cited
1990
Identification of the multiple beta-thalassemia mutations by denaturing gradient gel electrophoresis.
We used denaturing gradient gel electrophoresis to detect the beta-thalassemia mutations in the Chinese population. By amplifying… 
Highly Cited
1985
Highly Cited
1985
Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis.
The melting behavior of a DNA fragment carrying the mouse beta maj-globin promoter was investigated as a means of establishing… 
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