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Deamination

Known as: Deaminations 
The removal of an amino group (NH2) from a chemical compound.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The human cytidine deaminase APOBEC3G edits both nascent human immunodeficiency virus (HIV) and murine leukemia virus (MLV… Expand
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Highly Cited
2004
Highly Cited
2004
HIV-1 deleted for the vif accessory gene encapsidates the cellular cytidine deaminase APOBEC3G. Upon infection, the encapsidated… Expand
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Highly Cited
2003
Highly Cited
2003
Activation-induced cytidine deaminase (AID) is a protein required for B cells to undergo class switch recombination and somatic… Expand
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Highly Cited
2003
Highly Cited
2003
Somatic hypermutation and class switch recombination are DNA modification reactions that alter the genes encoding antibodies in B… Expand
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Highly Cited
2003
Highly Cited
2003
Viral replication usually requires that innate intracellular lines of defence be overcome, a task usually accomplished by… Expand
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Highly Cited
2001
Highly Cited
2001
We show that DNA molecules amplified by PCR from DNA extracted from animal bones and teeth that vary in age between 25 000 and… Expand
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Highly Cited
1999
Highly Cited
1999
In addition to its well-documented effects on gene silencing, cytosine methylation is a prominent cause of mutations. In humans… Expand
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Highly Cited
1990
Highly Cited
1990
Previously it has not been possible to determine the rate of deamination of cytosine in DNA at 37 degrees C because this reaction… Expand
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Highly Cited
1987
Highly Cited
1987
Although vertebrate DNA is generally depleted in the dinucleotide CpG, it has recently been shown that some vertebrate genes… Expand
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Highly Cited
1980
Highly Cited
1980
Spontaneous deamination converts cytosine to uracil, which is excised from DNA by the enzyme uracil-DNA glycosylase, leading to… Expand
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