Deamination

Known as: Deaminations 
The removal of an amino group (NH2) from a chemical compound.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
010020019362016

Papers overview

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Highly Cited
2011
Highly Cited
2011
DNA methylation is a major epigenetic mechanism for gene silencing. Whereas methyltransferases mediate cytosine methylation, it… (More)
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Highly Cited
2004
Highly Cited
2004
The human cytidine deaminase APOBEC3G edits both nascent human immunodeficiency virus (HIV) and murine leukemia virus (MLV… (More)
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Highly Cited
2004
Highly Cited
2004
HIV-1 deleted for the vif accessory gene encapsidates the cellular cytidine deaminase APOBEC3G. Upon infection, the encapsidated… (More)
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Highly Cited
2003
Highly Cited
2003
CEM15/APOBEC3G is a cellular protein required for resistance to infection by virion infectivity factor (Vif)-deficient human… (More)
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Highly Cited
2003
Highly Cited
2003
Activation-induced cytidine deaminase (AID), which is specific to B lymphocytes, is required for class switch recombination (CSR… (More)
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Highly Cited
2003
Highly Cited
2003
Activation-induced cytidine deaminase (AID) is a protein required for B cells to undergo class switch recombination and somatic… (More)
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Highly Cited
2002
Highly Cited
2002
After gene rearrangement, immunoglobulin variable genes are diversified by somatic hypermutation or gene conversion, whereas the… (More)
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Highly Cited
2001
Highly Cited
2001
We show that DNA molecules amplified by PCR from DNA extracted from animal bones and teeth that vary in age between 25 000 and… (More)
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Highly Cited
1999
Highly Cited
1999
In addition to its well-documented effects on gene silencing, cytosine methylation is a prominent cause of mutations. In humans… (More)
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Highly Cited
1980
Highly Cited
1980
Spontaneous deamination converts cytosine to uracil, which is excised from DNA by the enzyme uracil-DNA glycosylase, leading to… (More)
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