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DYNLRB1 gene

Known as: DNCL2A, dynein light chain roadblock-type 1, Dynein, Light Chain, Roadblock-Type 1 Gene 
This gene plays a role in intracellular transport.
National Institutes of Health

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DYNLRB1 wt Allele
Dynein Light Chain Roadblock-Type 1Homo sapiensIntracellular TransportLigand Binding
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome
Alpha-thalassemia X-linked intellectual disability (ATR-X) syndrome is caused by mutations in ATRX, which encodes a chromatin… Expand
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2016
2016
N-Acetyl-D-Glucosamine Kinase Interacts with Dynein-Lis1-NudE1 Complex and Regulates Cell Division
N-acetyl-D-glucosamine kinase (GlcNAc kinase or NAGK) primarily catalyzes phosphoryl transfer to GlcNAc during amino sugar… Expand
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2015
2015
N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points
N-acetylglucosamine kinase (GlcNAc kinase or NAGK) is a ubiquitously expressed enzyme in mammalian cells. Recent studies have… Expand
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Highly Cited
2014
Highly Cited
2014
Subunit composition of the human cytoplasmic dynein-2 complex
ABSTRACT Cytoplasmic dynein-2 is the motor for retrograde intraflagellar transport (IFT), and mutations in dynein-2 are known to… Expand
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2014
2014
Analysis of dynein intermediate chains, light intermediate chains and light chains in a cohort of hereditary peripheral neuropathies
The cytoplasmic dynein heavy chain (DYNC1H1) gene has been increasingly associated with neurodegenerative disorders including… Expand
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2009
2009
Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics.
BACKGROUND Solid malignant tumours are characterised by an inadequate vascular system, which can give rise to micro-regional… Expand
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2009
2009
Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier.
The reduced folate carrier (RFC) is a major folate transport system in mammalian cells. RFC is highly expressed in the intestine… Expand
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Highly Cited
2008
Highly Cited
2008
Rab6 family proteins interact with the dynein light chain protein DYNLRB1.
The small GTPase Rab6 is a key regulator in the retrograde transfer from endosomes via the Golgi to the ER. Three isoforms of… Expand
2006
2006
Crystal structure of human dynein light chain Dnlc2A: structural insights into the interaction with IC74.
The human light chain of the motor protein dynein, Dnlc2A, is also a novel TGF-beta-signaling component, which is altered with… Expand
Highly Cited
2001
Highly Cited
2001
Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients.
Two full-length cDNAs, DNLC2A and DNLC2B, were cloned and characterized. Their open reading frames respectively encode 96 amino… Expand
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