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DYNLRB1 gene

Known as: DNCL2A, dynein light chain roadblock-type 1, Dynein, Light Chain, Roadblock-Type 1 Gene 
This gene plays a role in intracellular transport.
National Institutes of Health

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DYNLRB1 wt Allele
Dynein Light Chain Roadblock-Type 1Homo sapiensIntracellular TransportLigand Binding

Papers overview

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Highly Cited
2018
Highly Cited
2018
Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome
Alpha-thalassemia X-linked intellectual disability (ATR-X) syndrome is caused by mutations in ATRX, which encodes a chromatin… 
2015
2015
N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points
N-acetylglucosamine kinase (GlcNAc kinase or NAGK) is a ubiquitously expressed enzyme in mammalian cells. Recent studies have… 
Highly Cited
2014
Highly Cited
2014
Subunit composition of the human cytoplasmic dynein-2 complex
ABSTRACT Cytoplasmic dynein-2 is the motor for retrograde intraflagellar transport (IFT), and mutations in dynein-2 are known to… 
Review
2011
Review
2011
The association of viral proteins with host cell dynein components during virus infection
After fusion with the cellular plasma membrane or endosomal membranes, viral particles are generally too large to diffuse freely… 
Review
2010
Review
2010
Characterisation of hairy cell leukaemia by tiling resolution array‐based comparative Genome hybridisation: a series of 13 cases and review of the literature
Little is known about the cytogenetic features and molecular mechanisms behind hairy cell leukaemia (HCL), despite the advances… 
2009
2009
Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics.
2009
2009
Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier.
The reduced folate carrier (RFC) is a major folate transport system in mammalian cells. RFC is highly expressed in the intestine… 
Highly Cited
2008
Highly Cited
2008
Rab6 family proteins interact with the dynein light chain protein DYNLRB1.
The small GTPase Rab6 is a key regulator in the retrograde transfer from endosomes via the Golgi to the ER. Three isoforms of… 
2006
2006
Crystal structure of human dynein light chain Dnlc2A: structural insights into the interaction with IC74.
Highly Cited
2001
Highly Cited
2001
Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients.
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