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DNA replication origin

National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Summary The integrity of eukaryotic genomes requires rapid and regulated chromatin replication. How this is accomplished is still… Expand
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Highly Cited
2015
Highly Cited
2015
Eukaryotic cells initiate DNA replication from multiple origins, which must be tightly regulated to promote precise genome… Expand
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Highly Cited
2015
Highly Cited
2015
To unveil the still-elusive nature of metazoan replication origins, we identified them genome-wide and at unprecedented high… Expand
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Highly Cited
2014
Highly Cited
2014
Summary The firing of eukaryotic origins of DNA replication requires CDK and DDK kinase activities. DDK, in particular, is… Expand
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Highly Cited
2009
Highly Cited
2009
The licensing of eukaryotic DNA replication origins, which ensures once-per-cell-cycle replication, involves the loading of six… Expand
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Highly Cited
2005
Highly Cited
2005
Eukaryotic chromatin structure limits the initiation of DNA replication spatially to chromosomal origin zones and temporally to… Expand
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Highly Cited
2004
Highly Cited
2004
In early Xenopus development, transcription is repressed and DNA replication initiates at non-specific sites. Here, we show that… Expand
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Highly Cited
1996
Highly Cited
1996
We describe several new cloning vectors for mutagenesis and allele replacement experiments. These plasmids have the R6K gamma DNA… Expand
Highly Cited
1990
Highly Cited
1990
Enzymatic synthesis of DNA from the simian virus 40 origin of DNA replication has been reconstituted in vitro with eight purified… Expand
Highly Cited
1982
Highly Cited
1982
The region at and near the simian virus 40 (SV40) DNA replication origin contains a series of palindromes, a 17-base pair (bp) A… Expand
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