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DNA replication origin

 
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
Summary The integrity of eukaryotic genomes requires rapid and regulated chromatin replication. How this is accomplished is still… Expand
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Highly Cited
2015
Highly Cited
2015
Eukaryotic cells initiate DNA replication from multiple origins, which must be tightly regulated to promote precise genome… Expand
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Highly Cited
2015
Highly Cited
2015
To unveil the still-elusive nature of metazoan replication origins, we identified them genome-wide and at unprecedented high… Expand
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Highly Cited
2014
Highly Cited
2014
Summary The firing of eukaryotic origins of DNA replication requires CDK and DDK kinase activities. DDK, in particular, is… Expand
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Highly Cited
2009
Highly Cited
2009
The licensing of eukaryotic DNA replication origins, which ensures once-per-cell-cycle replication, involves the loading of six… Expand
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Highly Cited
2007
Highly Cited
2007
DNA replication in archaea and in eukaryotes share many similarities. We report the structure of an archaeal origin recognition… Expand
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Highly Cited
2005
Highly Cited
2005
Eukaryotic chromatin structure limits the initiation of DNA replication spatially to chromosomal origin zones and temporally to… Expand
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Highly Cited
2004
Highly Cited
2004
In early Xenopus development, transcription is repressed and DNA replication initiates at non-specific sites. Here, we show that… Expand
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Highly Cited
1996
Highly Cited
1996
We describe several new cloning vectors for mutagenesis and allele replacement experiments. These plasmids have the R6K gamma DNA… Expand
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Highly Cited
1990
Highly Cited
1990
Enzymatic synthesis of DNA from the simian virus 40 origin of DNA replication has been reconstituted in vitro with eight purified… Expand
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