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DNA Replication Fork

DNA replication is a process that allows two new double helixes of DNA to be created from one double helix. During replication, Y-shaped regions of… 
National Institutes of Health

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2 relations
DNA polymerase iotaDNA replication origin

Papers overview

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2009
2009
Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1
DNA replication stress has been implicated in the etiology of genetic diseases, including cancers. It has been proposed that… 
2005
2005
Hedamycin, a DNA alkylator, induces (gamma)H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement.
Genotoxic treatments, such as UV light, camptothecin, and adozelesin, stall DNA replication and subsequently generate DNA strand… 
2004
2004
Subunit interaction and regulation of activity through terminal domains of the family D DNA polymerase from Pyrococcus horikoshii.
Family D DNA polymerase (PolD) has recently been found in the Euryarchaeota subdomain of Archaea. Its genes are adjacent to… 
Highly Cited
2001
Highly Cited
2001
UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.
Exposure to DNA-damaging agents triggers signal transduction pathways that are thought to play a role in maintenance of genomic… 
Review
1998
Review
1998
The development of combination therapy involving camptothecins: a review of preclinical and early clinical studies.
Highly Cited
1995
Highly Cited
1995
Recombinational rescue of the stalled DNA replication fork: a model based on analysis of an Escherichia coli strain with a chromosome region difficult to replicate
To examine the physiological effects of DNA replication arrest at the terminus (Ter), we constructed a replication-blocked… 
1991
1991
The priB and priC replication proteins of Escherichia coli. Genes, DNA sequence, overexpression, and purification.
1988
1988
DNA replication fork progression rate and temporal organization of S phase in normal epidermis and in basal cell carcinoma
The double‐pulse labeling technique for DNA fiber autoradiography was applied to epidermal cells from normal human skin and from… 
1987
1987
An analysis of DNA replication in synchronized CHO cells treated with benzo[a]pyrene diol epoxide.
1978
1978
Inactivation of phage repressor in a permeable cell system: role of recBC DNase in induction.
UV light causes inactivation of phage (phi80) repressor molecules in a plasmolyzed, permeable cell preparation of Escherichia… 
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