DNA Replication Fork

DNA replication is a process that allows two new double helixes of DNA to be created from one double helix. During replication, Y-shaped regions of… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
The protein Cdc45 plays a critical but poorly understood role in the initiation and elongation stages of eukaryotic DNA… (More)
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Highly Cited
2006
Highly Cited
2006
Cells respond to DNA replication stress by triggering cell cycle checkpoints, repair, or death. To understand the role of the DNA… (More)
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Review
2005
Review
2005
Three DNA polymerases are thought to function at the eukaryotic DNA replication fork. Currently, a coherent model has been… (More)
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Highly Cited
2005
Highly Cited
2005
Eukaryotic cells regulate the progression and integrity of DNA replication forks to maintain genomic stability and couple DNA… (More)
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Highly Cited
2001
Highly Cited
2001
The checkpoint kinase proteins Mec1 and Rad53 are required in the budding yeast, Saccharomyces cerevisiae, to maintain cell… (More)
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Highly Cited
2001
Highly Cited
2001
The stalling of DNA replication forks that occurs as a consequence of encountering DNA damage is a critical problem for cells… (More)
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Highly Cited
2000
Highly Cited
2000
Little is known about the DNA helicases required for the elongation phase of eukaryotic chromosome replication. Minichromosome… (More)
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Review
1998
Review
1998
Replication of the two template strands at eukaryotic cell DNA replication forks is a highly coordinated process that ensures… (More)
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Highly Cited
1996
Highly Cited
1996
Replication fork pause (RFP) sites transiently arresting replication fork movement were mapped to transfer RNA (tRNA) genes of… (More)
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Highly Cited
1994
Highly Cited
1994
Complete enzymatic replication of DNA from the simian virus 40 origin has been reconstituted with T antigen and highly purified… (More)
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