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DNA Mismatch Repair Protein PMS1

Known as: Rhabdomyosarcoma Antigen MU-RMS-40.10E, Human Homolog of Yeast mutL, Postmeiotic Segregation 1 
PMS1 protein homolog 1 (932 aa, ~106 kDa) is encoded by the human PMS1 gene. This protein is involved in the repair of DNA mismatches.
National Institutes of Health

Related topics

Related topics

10 relations
Cell NucleusDNA RepairDNA Repair GeneDNA-Binding Proteins

Papers overview

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Highly Cited
2004
Highly Cited
2004
Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1.
Recombination between moderately divergent DNA sequences is impaired compared with identical sequences. In yeast, an HO… 
Highly Cited
2000
Highly Cited
2000
MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability
DNA mismatch repair is important because of its role in maintaining genomic integrity and its association with hereditary non… 
Review
1999
Review
1999
Eukaryotic DNA mismatch repair.
Highly Cited
1999
Highly Cited
1999
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.
The yeast genome encodes four proteins (Pms1 and Mlh1-3) homologous to the bacterial mismatch repair component, MutL. Using two… 
Highly Cited
1998
Highly Cited
1998
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair
Germline mutations in the human MSH2, MLH1, PMS2 and PMS1 DNA mismatch repair (MMR) gene homologues appear to be responsible for… 
Highly Cited
1998
Highly Cited
1998
The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations.
The Saccharomyces cerevisiae genome encodes four MutL homologs. Of these, MLH1 and PMS1 are known to act in the MSH2-dependent… 
Highly Cited
1996
Highly Cited
1996
The mismatch repair system contributes to meiotic sterility in an interspecific yeast hybrid.
The mismatch repair system is the major barrier to genetic recombination during interspecific sexual conjugation in prokaryotes… 
Highly Cited
1994
Highly Cited
1994
MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast.
The discovery that mutations in DNA mismatch repair genes can cause hereditary nonpolyposis colorectal cancer has stimulated… 
Highly Cited
1994
Highly Cited
1994
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene
We have identified a new Saccharomyces cerevisiae gene, MLH1 (mutL homolog), that encodes a predicted protein product with… 
Highly Cited
1993
Highly Cited
1993
Pathway correcting DNA replication errors in Saccharomyces cerevisiae.
Mutation of predicted 3′‐‐>5′ exonuclease active site residues of Saccharomyces cerevisiae POL3 DNA polymerase (delta) or… 
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