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DNA Mismatch Repair Protein PMS1

Known as: Rhabdomyosarcoma Antigen MU-RMS-40.10E, Human Homolog of Yeast mutL, Postmeiotic Segregation 1 
PMS1 protein homolog 1 (932 aa, ~106 kDa) is encoded by the human PMS1 gene. This protein is involved in the repair of DNA mismatches.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Recombination between moderately divergent DNA sequences is impaired compared with identical sequences. In yeast, an HO… Expand
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Highly Cited
2000
Highly Cited
2000
DNA mismatch repair is important because of its role in maintaining genomic integrity and its association with hereditary non… Expand
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Review
1999
Review
1999
Eukaryotic mismatch repair (MMR) has been shown to require two different heterodimeric complexes of MutS-related proteins: MSH2… Expand
Highly Cited
1999
Highly Cited
1999
The yeast genome encodes four proteins (Pms1 and Mlh1-3) homologous to the bacterial mismatch repair component, MutL. Using two… Expand
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Highly Cited
1998
Highly Cited
1998
Germline mutations in the human MSH2, MLH1, PMS2 and PMS1 DNA mismatch repair (MMR) gene homologues appear to be responsible for… Expand
Highly Cited
1998
Highly Cited
1998
The Saccharomyces cerevisiae genome encodes four MutL homologs. Of these, MLH1 and PMS1 are known to act in the MSH2-dependent… Expand
Highly Cited
1996
Highly Cited
1996
The mismatch repair system is the major barrier to genetic recombination during interspecific sexual conjugation in prokaryotes… Expand
Highly Cited
1994
Highly Cited
1994
The discovery that mutations in DNA mismatch repair genes can cause hereditary nonpolyposis colorectal cancer has stimulated… Expand
Highly Cited
1994
Highly Cited
1994
We have identified a new Saccharomyces cerevisiae gene, MLH1 (mutL homolog), that encodes a predicted protein product with… Expand
Highly Cited
1993
Highly Cited
1993
Mutation of predicted 3′‐‐>5′ exonuclease active site residues of Saccharomyces cerevisiae POL3 DNA polymerase (delta) or… Expand