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DNA Gyrase

Known as: DNA Gyrase [Chemical/Ingredient], DNA-Gyrase 
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks… 
National Institutes of Health

Related topics

Related topics

10 relations

Narrower (2)

DNA Gyrase A SubunitDNA Gyrase B Subunit
In BloodProcess of secretionaspects of radiation effectschemical synthesis

Broader (2)

IsomeraseTopoisomerase II

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Development of a positive genetic selection system for inhibition of protein splicing using mycobacterial inteins in Escherichia coli DNA gyrase subunit A.
An intein-based positive genetic selection system was developed to study protein splicing and to provide a selection system with… 
1996
1996
Sequence analysis, purification, and study of inhibition by 4-quinolones of the DNA gyrase from Mycobacterium smegmatis
We determined the nucleotide sequence of a 6-kb DNA region harboring the recF, orf192, gyrB, and gyrA genes from Mycobacterium… 
Highly Cited
1993
Highly Cited
1993
Biological characterization of cyclothialidine, a new DNA gyrase inhibitor
Cyclothialidine is a new DNA gyrase inhibitor isolated from Streptomyces filipinensis NR0484. Structurally, it belongs to a new… 
Highly Cited
1989
Highly Cited
1989
Nuclease protection by Drosophila DNA topoisomerase II. Enzyme/DNA contacts at the strong topoisomerase II cleavage sites.
A DNA consensus sequence for topoisomerase II cleavage sites was derived previously based on a statistical analysis of the… 
Review
1988
Review
1988
DNA topoisomerases as targets for chemotherapy
DNA topoisomerases are ubiquitous enzymes that alter the configuration or topology of DNA. These enzymes play an important role… 
1987
1987
Antagonism of wild-type and resistant Escherichia coli and its DNA gyrase by the tricyclic 4-quinolone analogs ofloxacin and S-25930 stereoisomers
The mechanism of action of the quinolone analogs ofloxacin and S-25930, which are unusual because of the presence of a third ring… 
1984
1984
Intraphagocytic bactericidal activity of bacterial DNA gyrase inhibitors against Serratia marcescens.
Addition of phenylbutazone (2 mg/ml) to 55 vol% of fresh defibrinated human blood permitted leukocytic ingestion of Serratia… 
1984
1984
DNA binding and antigenic specifications of DNA gyrase.
Complexes of DNA gyrase and minichromosomal DNA containing the origin of replication of Escherichia coli (oriC) can be formed… 
Highly Cited
1982
Highly Cited
1982
Antagonism of the B subunit of DNA gyrase eliminates plasmids pBR322 and pMG110 from Escherichia coli
The constructed plasmid pBR322 and the native plasmid pMG110 were eliminated (cured) from growing Escherichia coli cells by the… 
1977
1977
Role of DNA gyrase in phiX replicative-form replication in vitro.
Preparations containing DNA gyrase activity Gellert, M., Mizuchi, K., O'Dea, M.H. & Nash, H.A. (1976) Proc. Natl. Acad. Sci. USA… 
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