DNA Gyrase

Known as: DNA Gyrase [Chemical/Ingredient], DNA-Gyrase 
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
05010019532017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Modulation of bacterial chromosomal supercoiling is a function of DNA gyrase-catalyzed strand breakage and rejoining. This… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Ciprofloxacin-resistant mutants of Streptococcus pneumoniae 7785 were generated by stepwise selection at increasing drug… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
The crystal structure of an N-terminal fragment of the Escherichia coli DNA gyrase B protein, complexed with a nonhydrolysable… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Nucleotide sequence analysis of the gyrA genes of 10 spontaneous quinolone-resistant gyrA mutants of Escherichia coli KL16… (More)
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Using the P4 unknotting assay, DNA topoisomerase II has been purified from several mammalian cells. Similar to prokaryotic DNA… (More)
Is this relevant?
Highly Cited
1983
Highly Cited
1983
DNA gyrase is the bacterial enzyme responsible for converting circular DNA to a negatively supercoiled form. We show that the… (More)
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Escherichia coli deletion mutants lacking DNA topoisomerase I have been identified previously and shown to grow at a normal rate… (More)
Is this relevant?
Highly Cited
1977
Highly Cited
1977
ATP-dependent DNA supercoiling catalyzed by Escherichia coli DNA gyrase was inhibited by oxolinic acid, a compound similar to but… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
1976
Highly Cited
1976
Relaxed closed-circular DNA is converted to negatively supercoiled DNA by DNA gyrase. This enzyme has been purified from… (More)
Is this relevant?
Highly Cited
1976
Highly Cited
1976
Novobiocin and coumermycin are known to inhibit the replication of DNA iing of DNA catalyzed by E. coli DNA gyrase, a recently… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?