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DMRT1 gene

Known as: DM domain expressed in testis 1, DOUBLESEX- AND MAB3-RELATED TRANSCRIPTION FACTOR 1, DMRT1 
This gene plays a role in male gonad development.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
We conducted a genome-wide association study for testicular germ cell tumor, genotyping 298,782 SNPs in 979 affected individuals… Expand
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Highly Cited
2010
Highly Cited
2010
The switch from mitosis to meiosis is a unique feature of germ cell development. In mammals, meiotic initiation requires retinoic… Expand
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Highly Cited
2009
Highly Cited
2009
Sex in birds is chromosomally based, as in mammals, but the sex chromosomes are different and the mechanism of avian sex… Expand
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Highly Cited
2005
Highly Cited
2005
Many basic cellular processes are shared across vast phylogenetic distances, whereas sex-determining mechanisms are highly… Expand
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Highly Cited
2004
Highly Cited
2004
The recent discovery of the DMY gene (DM domain gene on Y chromosome and one of the DMRT1 family genes) as a key determinant of… Expand
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Highly Cited
2002
Highly Cited
2002
The genes that determine the development of the male or female sex are known in Caenorhabditis elegans, Drosophila, and most… Expand
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Highly Cited
2000
Highly Cited
2000
The only molecular similarity in sex determination found so far among phyla is between the Drosophila doublesex (dsx) and… Expand
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Highly Cited
2000
Highly Cited
2000
DMRT1 has been suggested to be the first conserved gene involved in sex differentiation found from invertebrates to human. To… Expand
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Highly Cited
1999
Highly Cited
1999
Sex-determining mechanisms are highly variable between phyla. Only one example has been found in which structurally and… Expand
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Highly Cited
1999
Highly Cited
1999
Vertebrates exhibit a surprising array of sex-determining mechanisms, including X- and Y-chromosome heterogametes in male mammals… Expand
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