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DLK1 wt Allele

Known as: Delta-Like 1 Homolog (Drosophila) wt Allele, DLK, Pref-1 
Human DLK1 wild-type allele is located in the vicinity of 14q32 and is approximately 8 kb in length. This allele, which encodes protein delta homolog… 
National Institutes of Health

Related topics

Related topics

7 relations
14q32Intercellular Communication ProcessProtein Delta Homolog 1Signal Transduction

Broader (2)

DLK1 geneDLL1 gene

Papers overview

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Review
2009
Review
2009
Minireview: Pref-1: role in adipogenesis and mesenchymal cell fate.
Preadipocyte factor-1 [Pref-1; also called Dlk1 (Delta-like protein 1)] is made as an epidermal growth factor-repeat containing… 
Highly Cited
2005
Highly Cited
2005
Broiler performance and intestinal alterations when fed drug-free diets.
A study was carried out to investigate the effects of a drug-free feeding program on broiler performance and intestinal… 
Highly Cited
2004
Highly Cited
2004
Regulation of Human Skeletal Stem Cells Differentiation by Dlk1/Pref‐1
Dlk‐1/Pref‐1 was identified as a novel regulator of human skeletal stem cell differentiation. Dlk1/Pref‐1 is expressed in bone… 
Highly Cited
2004
Highly Cited
2004
Transit-amplifying ductular (oval) cells and their hepatocytic progeny are characterized by a novel and distinctive expression of delta-like protein/preadipocyte factor 1/fetal antigen 1.
Highly Cited
2004
Highly Cited
2004
Specification of vertebral identity is coupled to Notch signalling and the segmentation clock
To further analyse requirements for Notch signalling in patterning the paraxial mesoderm, we generated transgenic mice that… 
Highly Cited
2003
Highly Cited
2003
Isolation of hepatoblasts based on the expression of Dlk/Pref-1
Hepatoblasts are common progenitors for hepatocytes and biliary epithelial cells, although their nature remains largely unknown… 
Highly Cited
2000
Highly Cited
2000
A Role for Pref-1 and HES-1 in Thymocyte Development
T lymphocyte development requires a series of interactions between developing thymocytes and thymic epithelial (TE) cells. In… 
Highly Cited
1999
Highly Cited
1999
Transcriptional Repression of pref-1 by Glucocorticoids Promotes 3T3-L1 Adipocyte Differentiation*
Pref-1 is an epidermal growth factor-like domain-containing transmembrane protein that is cleaved to generate a soluble factor… 
Highly Cited
1999
Highly Cited
1999
Adipocyte differentiation is modulated by secreted delta-like (dlk) variants and requires the expression of membrane-associated dlk.
Previous studies demonstrate that the delta-like (dlk) and preadipocyte factor 1 (Pref-1) genes encode similar proteins. Pref-1… 
Highly Cited
1997
Highly Cited
1997
TNFα-Mediated Inhibition and Reversal of Adipocyte Differentiation Is Accompanied by Suppressed Expression of PPARγ without Effects on Pref-1 Expression.
Tumor necrosis factor α (TNFα) is a polypeptide hormone with pleiotropic effects on cellular proliferation and differentiation… 
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