DEFA1 gene

Known as: RETROCYCLIN, HUMAN NEUTROPHIL PEPTIDE 1, HUMAN NEUTROPHIL PEPTIDE 2 
 
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
We have defined unexpectedly extensive copy number variation at the human anti-microbial alpha-defensin genes DEFA1 and DEFA3… (More)
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Highly Cited
2005
Highly Cited
2005
In order to study mechanisms and regulation of RNA polymerase II (RNAPII) ubiquitylation and degradation, highly purified factors… (More)
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Highly Cited
2004
Highly Cited
2004
We tested the ability of 20 synthetic theta defensins to protect cells from infection by type 1 and type 2 herpes simplex viruses… (More)
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Highly Cited
2003
Highly Cited
2003
Theta-defensins are circular octadecapeptides that contain an internal tridisulfide ladder. Because retrocyclin-1, an ancestral… (More)
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Highly Cited
2003
Highly Cited
2003
Retrocyclin is a circular antimicrobial 18-residue peptide encoded in the human genome by a theta-defensin pseudogene. In the… (More)
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Highly Cited
2002
Highly Cited
2002
Human bone marrow expresses a pseudogene that encodes an antimicrobial peptide homologous to rhesus monkey circular minidefensins… (More)
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Highly Cited
2002
Highly Cited
2002
Eukaryotic cells use multiple, highly conserved mechanisms to contend with ultraviolet-light-induced DNA damage. One important… (More)
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Highly Cited
1994
Highly Cited
1994
Cryptdins are antimicrobial peptides of the defensin family that are produced by intestinal Paneth cells. mRNAs encoding 17… (More)
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Highly Cited
1992
Highly Cited
1992
Five intestinal defensins, termed cryptdins 1-5, have been purified from mouse small bowel, sequenced, and localized to the… (More)
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Highly Cited
1986
Highly Cited
1986
Human neutrophils contain a family of microbicidal peptides known as defensins. One of these defensins, human neutrophil peptide… (More)
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