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DEFA1 gene

Known as: RETROCYCLIN, HUMAN NEUTROPHIL PEPTIDE 1, HUMAN NEUTROPHIL PEPTIDE 2 
National Institutes of Health

Related topics

Related topics

5 relations
DEFA1A3 geneDEFA3 genecryptdinhuman neutrophil peptide 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Def1 and Dst1 play distinct roles in repair of AP lesions in highly transcribed genomic regions.
2011
2011
Correlation of DEFA1 Gene Copy Number Variation with Intestinal Involvement in Behcet's Disease
Copy number variation has been associated with various autoimmune diseases. We investigated the copy number (CN) of the DEFA1… 
2008
2008
Postnatal changes in the expression of genes for cryptdins 1-6 and the role of luminal bacteria in cryptdin gene expression in mouse small intestine.
Although there have been many fascinating studies on cryptdins, the information for each cryptdin isoform was not completely… 
2008
2008
Human α- and β-Defensins Bind to Immobilized Adhesins from Porphyromonas gingivalis
ABSTRACT Human neutrophil peptide α-defensins (HNPs) and human β-defensins (HBDs) are small well-characterized peptides with… 
2007
2007
Alpha Defensins 1, 2, and 3: Potential Roles in Dyslipidemia and Vascular Dysfunction in Humans
Objectives—&agr;-Defensins are natural antibiotics made by neutrophils that have been reported to modulate cholesterol metabolism… 
Highly Cited
2006
Highly Cited
2006
θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation*
Retrocyclin-1, a θ-defensin, protects target cells from human immunodeficiency virus, type 1 (HIV-1) by preventing viral entry… 
Highly Cited
2001
Highly Cited
2001
Human alpha-defensin 1 (HNP-1) inhibits adenoviral infection in vitro.
Adenoviral gene transfer is a promising tool for direct treatment of cystic fibrosis by local application of the CFTR-gene via… 
2001
2001
Cryptdin-3 induces novel apical conductance(s) in Cl- secretory, including cystic fibrosis, epithelia.
Opening of anion-conductive pathways in apical membranes of secretory cells lining mucosal surfaces is a critical step in salt… 
Highly Cited
2000
Highly Cited
2000
Antibacterial activity of human neutrophil peptide-1 against Mycobacterium tuberculosis H37Rv: in vitro and ex vivo study.
The aim of the study was to investigate the activity of human neutrophil peptide (HNP)-1 to kill Mycobacterium tuberculosis H37Rv… 
Highly Cited
2000
Highly Cited
2000
Endonuclease activity in lipocalins.
Several lipocalins contain conserved amino acid sequences similar to the phosphodiester bond cleavage domain of sugar non… 
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