DEFA3 gene

Known as: DEFENSIN, ALPHA, 3, DEF3, HNP3 
 
National Institutes of Health

Related topics

Related topics

7 relations
DEF6 geneDEFA1 geneDEFA1A3 geneDEFA4 gene
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Papers overview

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2010
2010
Antibacterial and lipopolysaccharide (LPS)-neutralising activity of human cationic antimicrobial peptides against periodontopathogens.
In this study, we investigated the antibacterial activity of eight antimicrobial peptides (AMPs), comprising four human beta… (More)
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Highly Cited
2007
Highly Cited
2007
Chemoattraction of macrophages, T lymphocytes, and mast cells is evolutionarily conserved within the human alpha-defensin family.
Human defensins are natural peptide antibiotics. On the basis of the position and bonding of six conserved cysteine residues… (More)
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Highly Cited
2006
Highly Cited
2006
Crystal structures of human alpha-defensins HNP4, HD5, and HD6.
Six alpha-defensins have been found in humans. These small arginine-rich peptides play important roles in various processes… (More)
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Highly Cited
2005
Highly Cited
2005
Antibacterial activity and specificity of the six human {alpha}-defensins.
We developed a kinetic, 96-well turbidimetric procedure that is capable of testing the antimicrobial properties of six human… (More)
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2005
2005
Antibacterial Activity and Specificity of the Six Human α-Defensins
We developed a kinetic, 96-well turbidimetric procedure that is capable of testing the antimicrobial properties of six human… (More)
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1999
1999
Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes.
Experiments to isolate and characterize rhesus macaque myeloid alpha-defensins (RMADs) were conducted. Seven RMAD peptides were… (More)
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Highly Cited
1996
Highly Cited
1996
Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils.
Reports that interleukin-8 (IL-8) induces the infiltration of neutrophils followed by T-cells into injection sites led us to… (More)
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1996
1996
Evaluation of susceptibility of gram-positive and -negative bacteria to human defensins by using radial diffusion assay.
Defensins are small cationic bactericidal peptides present abundantly in the granules of polymorphonuclear neutrophils (PMNs… (More)
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Highly Cited
1989
Highly Cited
1989
Monocyte-chemotactic activity of defensins from human neutrophils.
We investigated the monocyte-chemotactic activity of fractionated extracts of human neutrophil granules. Monocyte-chemotactic… (More)
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Highly Cited
1986
Highly Cited
1986
Direct inactivation of viruses by human granulocyte defensins.
Human neutrophils contain a family of microbicidal peptides known as defensins. One of these defensins, human neutrophil peptide… (More)
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