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DEFA3 gene
Known as:
DEFENSIN, ALPHA, 3
, DEF3
, HNP3
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National Institutes of Health
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Related topics
Related topics
7 relations
DEF6 gene
DEFA1 gene
DEFA1A3 gene
DEFA4 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Chemoattraction of Macrophages, T Lymphocytes, and Mast Cells Is Evolutionarily Conserved within the Human α-Defensin Family1
J. Grigat
,
A. Soruri
,
U. Forssmann
,
J. Riggert
,
J. Zwirner
Journal of Immunology
2007
Corpus ID: 39249092
Human defensins are natural peptide antibiotics. On the basis of the position and bonding of six conserved cysteine residues…
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Highly Cited
2006
Highly Cited
2006
Crystal structures of human α‐defensins HNP4, HD5, and HD6
A. Szyk
,
Zhibin Wu
,
K. Tucker
,
De Yang
,
Wuyuan Lu
,
J. Lubkowski
Protein Science
2006
Corpus ID: 45883256
Six α‐defensins have been found in humans. These small arginine‐rich peptides play important roles in various processes related…
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Highly Cited
2005
Highly Cited
2005
Antibacterial Activity and Specificity of the Six Human α-Defensins
Bryan Ericksen
,
Zhibin Wu
,
Wuyuan Lu
,
R. Lehrer
Antimicrobial Agents and Chemotherapy
2005
Corpus ID: 10355240
ABSTRACT We developed a kinetic, 96-well turbidimetric procedure that is capable of testing the antimicrobial properties of six…
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Highly Cited
2005
Highly Cited
2005
Antibacterial activity and specificity of the six human {alpha}-defensins.
Bryan Ericksen
,
Zhibin Wu
,
Wuyuan Lu
,
R. Lehrer
Antimicrobial Agents and Chemotherapy
2005
Corpus ID: 29999864
We developed a kinetic, 96-well turbidimetric procedure that is capable of testing the antimicrobial properties of six human…
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Highly Cited
1999
Highly Cited
1999
Isolation, Characterization, cDNA Cloning, and Antimicrobial Properties of Two Distinct Subfamilies of α-Defensins from Rhesus Macaque Leukocytes
Yiquan Tang
,
Jun Yuan
,
C. Miller
,
M. Selsted
Infection and Immunity
1999
Corpus ID: 23761710
ABSTRACT Experiments to isolate and characterize rhesus macaque myeloid α-defensins (RMADs) were conducted. Seven RMAD peptides…
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Highly Cited
1996
Highly Cited
1996
Identification of Defensin-1, Defensin-2, and CAP37/Azurocidin as T-cell Chemoattractant Proteins Released from Interleukin-8-stimulated Neutrophils (*)
O. Chertov
,
D. Michiel
,
+6 authors
J. Oppenheim
Journal of Biological Chemistry
1996
Corpus ID: 42802481
Reports that interleukin-8 (IL-8) induces the infiltration of neutrophils followed by T-cells into injection sites led us to…
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Highly Cited
1989
Highly Cited
1989
Monocyte-chemotactic activity of defensins from human neutrophils.
M. Territo
,
T. Ganz
,
M. Selsted
,
R. Lehrer
Journal of Clinical Investigation
1989
Corpus ID: 21175789
We investigated the monocyte-chemotactic activity of fractionated extracts of human neutrophil granules. Monocyte-chemotactic…
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Highly Cited
1988
Highly Cited
1988
Inhibition of protein kinase C by defensins, antibiotic peptides from human neutrophils.
P. Charp
,
W. Rice
,
+6 authors
J. Kuo
Biochemical Pharmacology
1988
Corpus ID: 38908001
Highly Cited
1986
Highly Cited
1986
Direct inactivation of viruses by human granulocyte defensins
K. Daher
,
M. Selsted
,
R. Lehrer
Journal of Virology
1986
Corpus ID: 45679114
Human neutrophils contain a family of microbicidal peptides known as defensins. One of these defensins, human neutrophil peptide…
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Highly Cited
1985
Highly Cited
1985
Defensins. Natural peptide antibiotics of human neutrophils.
T. Ganz
,
M. Selsted
,
+4 authors
R. Lehrer
Journal of Clinical Investigation
1985
Corpus ID: 3518587
We extracted a granule-rich sediment from normal human neutrophils and subjected it to chromatographic, electrophoretic, and…
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