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DDIT3 wt Allele

Known as: Growth Arrest- and DNA Damage-Inducible 153 Gene, C/EBP Zeta Gene, CHOP10 
Human DDIT3 wild-type allele is located within 12q13.1-q13.2 and is approximately 4 kb in length. This allele, which encodes DNA damage-inducible… 
National Institutes of Health

Related topics

Related topics

9 relations
Chromosomal translocationEndoplasmic Reticulum Degradation PathwayMAPK Signaling PathwayMyxoid/Round Cell Liposarcoma

Broader (1)

DDIT3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Selenium Decreases Thyroid Cancer Cell Growth by Increasing Expression of GADD153 and GADD34
Selenium (Se) supplementation is reported to decrease the incidence and total mortality of cancer. Whereas in vitro and in vivo… 
2008
2008
TRE-dependent transcription activation by JDP2–CHOP10 association
The c-Jun dimerization protein 2, JDP2, is a member of the activating protein 1 (AP-1) family of transcription factors… 
Highly Cited
2006
Highly Cited
2006
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells.
Celecoxib, a selective cyclooxygenase 2 inhibitor, is known to have anti-inflammatory activity and to induce apoptosis in various… 
Highly Cited
2004
Highly Cited
2004
Curcumin-induced GADD153 gene up-regulation in human colon cancer cells.
Ingestion of plant products containing the phenolic phytochemical, curcumin, has been linked to lower incidences of colon cancer… 
Review
2004
Review
2004
Molecular Mechanisms of Fenretinide‐Induced Apoptosis of Neuroblastoma Cells
Abstract: Synthetic retinoids such as fenretinide [N‐(4‐hydroxyphenyl)retinamide] induce apoptosis of neuroblastoma cells, act… 
Review
2003
Review
2003
Induction of GADD153 and Bak: novel molecular targets of fenretinide-induced apoptosis of neuroblastoma.
2002
2002
Genes associated with pro-apoptotic and protective mechanisms are affected differently on exposure of neuronal cell cultures to arsenite. No indication for endoplasmic reticulum stress despite…
2002
2002
Specific up‐regulation of GADD153/CHOP in 1‐methyl‐4‐phenyl‐pyridinium‐treated SH‐SY5Y cells
Growth arrest DNA damage‐inducible 153 (GADD153) expression was increased in 1‐methyl‐4‐phenyl‐pyridinium (MPP+)‐treated human SH… 
2002
2002
Expression and transactivating functions of the bZIP transcription factor GADD153 in mammary epithelial cells
Heregulin-β1 (HRG), a combinatorial ligand for human epidermal growth factor receptor 3 (HER3) and HER4, is a regulatory… 
1994
1994
Calcium mediates expression of stress‐response genes in prostaglandin A2‐induced growth arrest
We have explored the mechanisms involved in the induction of five stress‐response genes (heme oxygenase [HO], c‐fos, Egr‐1… 
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