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DDIT3 wt Allele

Known as: Growth Arrest- and DNA Damage-Inducible 153 Gene, C/EBP Zeta Gene, CHOP10 
Human DDIT3 wild-type allele is located within 12q13.1-q13.2 and is approximately 4 kb in length. This allele, which encodes DNA damage-inducible… 
National Institutes of Health

Related topics

Related topics

9 relations
Chromosomal translocationEndoplasmic Reticulum Degradation PathwayMAPK Signaling PathwayMyxoid/Round Cell Liposarcoma

Broader (1)

DDIT3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Targeting proteasomal pathways by dietary curcumin for cancer prevention and treatment.
Curcumin, a major component of the golden spice turmeric (Curcuma longa), has been linked with the prevention and treatment of a… 
Highly Cited
2013
Highly Cited
2013
Upregulation of CHOP/GADD153 during Coronavirus Infectious Bronchitis Virus Infection Modulates Apoptosis by Restricting Activation of the Extracellular Signal-Regulated Kinase Pathway
ABSTRACT Induction of the unfolded protein response (UPR) is an adaptive cellular response to endoplasmic reticulum (ER) stress… 
Highly Cited
2006
Highly Cited
2006
Activation and Cross-talk between Akt, NF-κB, and Unfolded Protein Response Signaling in 1-LN Prostate Cancer Cells Consequent to Ligation of Cell Surface-associated GRP78*
Binding of activated forms of the proteinase inhibitor α2-macroglobulin (α2M*) to cell surface-associated GRP78 on 1-LN human… 
Highly Cited
2005
Highly Cited
2005
Multiple Signals Induce Endoplasmic Reticulum Stress in Both Primary and Immortalized Chondrocytes Resulting in Loss of Differentiation, Impaired Cell Growth, and Apoptosis*
The endoplasmic reticulum is the site of synthesis and folding of secretory proteins and is sensitive to changes in the internal… 
Highly Cited
2003
Highly Cited
2003
Isoliquiritigenin inhibits the growth of prostate cancer.
Highly Cited
2003
Highly Cited
2003
Intracellular mechanisms of cyclosporin A-induced tubular cell apoptosis.
Tubular cell apoptosis contributes to the pathogenesis of renal injury. However, the intracellular pathways that are active in… 
Highly Cited
2001
Highly Cited
2001
Repression of GADD153/CHOP by NF-κB: a possible cellular defense against endoplasmic reticulum stress-induced cell death
Exposure of mammalian cells to ultraviolet light, nutrient deprived culture media, hypoxia, environmental toxicants such as… 
Highly Cited
1996
Highly Cited
1996
Physical and Functional Association between GADD153 and CCAAT/Enhancer-binding Protein β during Cellular Stress*
GADD153, a ubiquitously expressed member of the CCAAT/enhancer-binding protein (C/EBP) family is induced by a wide variety of… 
Highly Cited
1994
Highly Cited
1994
Genotoxic stress confers preferential and coordinate messenger RNA stability on the five gadd genes.
The growth arrest and DNA damage-inducible (gadd) genes represent a group of five stress-inducible genes that are coordinately… 
Highly Cited
1992
Highly Cited
1992
Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage.
Accumulation of gadd153 mRNA is strongly stimulated in mammalian cells by treatments which arrest growth or damage DNA (A. J… 
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