DDIT3 gene

Known as: DNA-Damage-Inducible Transcript 3 Gene, CHOP10, GROWTH ARREST- AND DNA DAMAGE-INDUCIBLE GENE GADD153 
This gene plays a role in the modulation of transcription.

Topic mentions per year

Topic mentions per year

1992-2018
010203019922018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
There is increasing evidence that neuron death in neurodegenerative diseases, such as Parkinson's disease, is due to the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Hypoxia is a key factor in tumor development, contributing to angiogenesis and radiotherapy resistance. Hypoxia-inducible factor… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The sesquiterpene lactone parthenolide, the principal active component in medicinal plants, has been used conventionally to treat… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Protein kinases that phosphorylate the alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) are activated in stressed… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Alterations in the cellular redox potential by homocysteine promote endothelial cell (EC) dysfunction, an early event in the… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
In the present study, we show that Fas receptor ligation or cellular treatment with synthetic C6-ceramide results in activation… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The gene encoding C/EBP-homologous protein (CHOP), also known as growth arrest and DNA-damage-inducible gene 153 (GADD153), is… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
CHOP (GADD153) is a member of the C/EBP family and a stress-induced protein. To investigate the role of CHOP in cellular growth… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
We have investigated 234 tumors of the central nervous system for amplification of 9 different loci from 12q13-14 and report that… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The growth arrest and DNA damage-inducible gene CHOP (GADD153) encodes a small nuclear protein from the C/EBP family, originally… (More)
Is this relevant?