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DDIT3 gene

Known as: DNA-Damage-Inducible Transcript 3 Gene, CHOP10, GROWTH ARREST- AND DNA DAMAGE-INDUCIBLE GENE GADD153 
This gene plays a role in the modulation of transcription.
National Institutes of Health

Related topics

Related topics

10 relations
Chromosomal translocationDDIT4 geneFUS-DDIT3 Fusion Protein ExpressionMyxoid/Round Cell Liposarcoma

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DDIT3 wt Allele

Papers overview

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2013
2013
Combined treatment with SAHA, bortezomib, and clarithromycin for concomitant targeting of aggresome formation and intracellular proteolytic pathways enhances ER stress-mediated cell death in breast…
2009
2009
Chemotherapeutic sensitization by endoplasmic reticulum stress: Increasing the efficacy of taxane against prostate cancer
Taxanes are first line drugs for treating prostate cancer recurrence after the failure of anti-androgen therapy. There is a need… 
Highly Cited
2005
Highly Cited
2005
Endoplasmic reticulum stress signal mediators are targets of selenium action.
A monomethylated selenium metabolite, called methylseleninic acid (MSA), has recently been shown to cause global thiol redox… 
Highly Cited
2004
Highly Cited
2004
Curcumin-induced GADD153 gene up-regulation in human colon cancer cells.
Ingestion of plant products containing the phenolic phytochemical, curcumin, has been linked to lower incidences of colon cancer… 
Highly Cited
2004
Highly Cited
2004
Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro
Abstract The dietary phytochemical indole-3-carbinol (I3C) protects against cervical cancer in animal model studies and in human… 
2002
2002
Genes associated with pro-apoptotic and protective mechanisms are affected differently on exposure of neuronal cell cultures to arsenite. No indication for endoplasmic reticulum stress despite…
Highly Cited
2001
Highly Cited
2001
Genes regulated in human breast cancer cells overexpressing manganese-containing superoxide dismutase.
Highly Cited
2000
Highly Cited
2000
Novel Interaction between the Transcription Factor CHOP (GADD153) and the Ribosomal Protein FTE/S3a Modulates Erythropoiesis*
The transcription factor CHOP (GADD153) heterodimerizes with other C/EBP family members, especially C/EBPβ, thus preventing their… 
Highly Cited
1999
Highly Cited
1999
Glutamine Deprivation Induces the Expression ofGADD45 and GADD153 Primarily by mRNA Stabilization*
The expression of the growtharrest- and DNA damage-inducible genes, GADD45 and GADD153/CHOP(C/EBP-homologous protein), as well as… 
Highly Cited
1994
Highly Cited
1994
The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas.
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