FUS-DDIT3 Fusion Protein Expression
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Myxoid liposarcomas (MLS), malignant tumors of adipocyte origin, are driven by the FUS‐DDIT3 fusion gene encoding an aberrant… Expand Myxoid liposarcoma is a malignant lipogenic tumor that develops in deep soft tissues. While local control rates are good, current… Expand Numerous gene fusions have been uncovered across multiple cancer types. Although the ability to target several of these fusions… Expand Fusion oncogenes are among the most common types of oncogene in human cancers. The gene rearrangements result in new combinations… Expand Myxoid liposarcomas (MLSs) with extensive lipoma-like changes (MLSLC) are rare, and it is often difficult to distinguish them… Expand Myxoid liposarcoma with or without a round cell component is the most common subtype of liposarcoma. The diagnosis of myxoid… Expand BackgroundMyxoid liposarcoma is a relatively common malignant soft tissue tumor, characterized by a (12;16) translocation… Expand Background FUS-DDIT3 is a chimeric protein generated by the most common chromosomal translocation t(12;16)(q13;p11) linked to… Expand Myxoid/round cell liposarcoma (MLS/RCLS) is the most common subtype of liposarcoma. Most MLS/RCLS carry a t(12;16) translocation… Expand The myxoid/round cell liposarcoma oncogene FUS‐DDIT3 is the result of a translocation derived gene fusion between the splicing… Expand