DARPP
National Institutes of Health
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Lung cancer is the leading cause of cancer-related death worldwide. Here we demonstrate that elevated expression of dopamine and…
Dopamine and cAMP-regulated phosphoprotein Mr 32,000 (DARPP-32), also known as phosphoprotein phosphatase-1 regulatory subunit 1B…
Esophageal adenocarcinoma (EAC) is an aggressive malignancy with a poor outcome. Although targeting ERBB2 with trastuzumab has…
BackgroundTruncated dopamine and cyclic-AMP-regulated phosphoprotein (t-DARPP) is frequently overexpressed in gastrointestinal…
Attention deficit/hyperactivity disorder (ADHD) is characterized by inattention, impulsivity, and motor hyperactivity. Several…
BackgroundRecent reports have shown that t-DARPP (truncated isoform of DARPP-32) can mediate trastuzumab resistance in breast…
Purpose: We have investigated the role of t-DARPP in trastuzumab resistance in ERBB2-amplified and overexpressed breast cancer…
Dopamine and cAMP‐regulated phosphoprotein (DARPP)‐32 is a phosphoprotein that is centrally involved in dopamine signalling…
Gastric carcinoma is the second most common cause of cancer-related death worldwide. Recently, we have demonstrated that…