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DARPP

 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

DopaminePhosphoproteins

Narrower (1)

Dopamine and cAMP-Regulated Phosphoprotein 32

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
DARPP-32: from neurotransmission to cancer
Dopamine and cAMP-regulated phosphoprotein Mr 32,000 (DARPP-32), also known as phosphoprotein phosphatase-1 regulatory subunit 1B… Expand
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2016
2016
Human t-DARPP is induced during striatal development
Human Dopamine- and cAMP-regulated phosphoprotein of molecular weight 32kDa (DARPP-32, also known as PPP1R1B) gene codes for… Expand
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2012
2012
Regulation of ERBB2 receptor by t-DARPP mediates trastuzumab resistance in human esophageal adenocarcinoma.
Esophageal adenocarcinoma (EAC) is an aggressive malignancy with a poor outcome. Although targeting ERBB2 with trastuzumab has… Expand
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Highly Cited
2010
Highly Cited
2010
Role of Aberrant Striatal Dopamine D1 Receptor/cAMP/Protein Kinase A/DARPP32 Signaling in the Paradoxical Calming Effect of Amphetamine
Attention deficit/hyperactivity disorder (ADHD) is characterized by inattention, impulsivity, and motor hyperactivity. Several… Expand
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2010
2010
t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer
BackgroundRecent reports have shown that t-DARPP (truncated isoform of DARPP-32) can mediate trastuzumab resistance in breast… Expand
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2010
2010
Regulation of β-catenin by t-DARPP in upper gastrointestinal cancer cells
BackgroundTruncated dopamine and cyclic-AMP-regulated phosphoprotein (t-DARPP) is frequently overexpressed in gastrointestinal… Expand
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2008
2008
Expression of t-DARPP Mediates Trastuzumab Resistance in Breast Cancer Cells
Purpose: We have investigated the role of t-DARPP in trastuzumab resistance in ERBB2-amplified and overexpressed breast cancer… Expand
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2005
2005
Overexpression of DARPP‐32 in colorectal Adenocarcinoma
Dopamine and cAMP‐regulated phosphoprotein (DARPP)‐32 is a phosphoprotein that is centrally involved in dopamine signalling… Expand
Highly Cited
2002
Highly Cited
2002
Gastric cancers overexpress DARPP-32 and a novel isoform, t-DARPP.
Gastric carcinoma is the second most common cause of cancer-related death worldwide. Recently, we have demonstrated that… Expand
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Highly Cited
2002
Highly Cited
2002
Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1
BACKGROUND Modulation of protein phosphorylation by dopamine is thought to play an important role in drug reward. Protein… Expand
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