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The impact of physical activity on psychological health during Covid-19 pandemic in Italy
Memory-specific temporal profiles of gene expression in the hippocampus
- S. Cavallaro, V. D’Agata, P. Manickam, F. Dufour, D. Alkon
- Biology, PsychologyProceedings of the National Academy of Sciences…
- 2 December 2002
Results of this study suggest that while learning and physical activity involve common groups of genes, the behavior of learning and memory emerges from unique patterns of gene expression across time.
Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia
Curcumin activates defensive genes and protects neurons against oxidative stress.
This study gives additional support to the possible use of curcumin as a dietary preventive agent against oxidative stress-related diseases.
Gene expression profiles of heme oxygenase isoforms in the rat brain
The Major Green Tea Polyphenol, (-)-Epigallocatechin-3-Gallate, Induces Heme Oxygenase in Rat Neurons and Acts as an Effective Neuroprotective Agent against Oxidative Stress
- L. Romeo, M. Intrieri, G. Scapagnini
- BiologyJournal of the American College of Nutrition
- 1 August 2009
It is demonstrated that EGCG, the major green tea catechin, induced HO-1 expression in cultured neurons, possibly by activation of the transcription factor Nrf2, and by this mechanism was able to protect against oxidative stress–induced cell death.
Potential role of probiotics on colorectal cancer prevention
Several mechanisms could explain the preventive action of probiotics against colorectal cancer onset: alteration of the intestinal microflora; inactivation of cancerogenic compounds; competition with putrefactive and pathogenic microbiota; improvement of the host’s immune response; and inhibition of tyrosine kinase signaling pathways.
Curcumin prevents high glucose damage in retinal pigment epithelial cells through ERK1/2‐mediated activation of the Nrf2/HO‐1 pathway
It is demonstrated that curcumin provides protection against HG‐induced damage in RPE cells through the activation of Nrf2/HO‐1 signaling that involves the ERK pathway, suggesting thatCurcumin may have therapeutic value in the treatment of diabetic retinopathy.
Pituitary adenylate cyclase activating polypeptide prevents apoptosis in cultured cerebellar granule neurons.
The activation of type I PACAP receptors may contribute to the survival of cerebellar granule neurons by reducing the development of apoptosis in a dose-dependent manner.
Dopamine D3 Receptor Is Necessary for Ethanol Consumption: An Approach with Buspirone
DA signaling via D3R is essential for ethanol-related reward and consumption and may represent a novel therapeutic target for weaning and evaluated buspirone, an approved drug for anxiety disorders endowed with D3 R antagonist activity, that resulted effective in inhibiting ethanol intake.