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DAB(486)-interleukin 2

Known as: DAB(486)-IL-2, DAB486-IL-2, interleukin 2 toxin 
National Institutes of Health

Papers overview

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Review
1995
Review
1995
The results from the phase I/II studies of the intravenous administration of DAB486-IL-2 to patients with refractory… 
1992
1992
Insulin‐dependent diabetes mellitus (IDDM) is strikingly similar in the non‐obese diabetic (NOD) mouse and humans. In IDDM, the… 
1992
1992
Early murine fetal thymocytes express functional, high affinity IL-2 receptors as determined by: (i) the presence of IL-2R beta… 
1991
1991
We have used site-directed insertion and point mutagenesis in an attempt to increase the cytotoxic potency and receptor-binding… 
Highly Cited
1990
Highly Cited
1990
We have used site-directed mutagenesis to examine the role played by Arg191, Arg193, and Arg194 of the fusion toxin DAB486-IL-2… 
1990
1990
During the proliferative burst after Ag recognition, T cells express cell-surface, high-affinity IL-2R. The importance of IL-2R…