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D-Pen2, L-Pen5-Enkephalin
Known as:
D Pen2, L Pen5 Enkephalin
, DPLPE
, L-Pen5-Enkephalin D-Pen2
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Cyclic Opioid Peptides.
Michael Remesic
,
Y. Lee
,
V. Hruby
Current Medicinal Chemistry
2016
Corpus ID: 441105
For decades the opioid receptors have been an attractive therapeutic target for the treatment of pain. Since the first discovery…
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Highly Cited
1999
Highly Cited
1999
The effect of halogenation on blood–brain barrier permeability of a novel peptide drug☆
C. Gentry
,
R. Egleton
,
+4 authors
T. Davis
Peptides
1999
Corpus ID: 34381737
1993
1993
Selective and interactive down-regulation of mu- and delta-opioid receptors in human neuroblastoma SK-N-SH cells.
Y. Baumhaker
,
M. Gafni
,
O. Keren
,
Y. Sarne
Molecular Pharmacology
1993
Corpus ID: 23012861
Human neuroblastoma SK-N-SH cells, which contain both mu- and delta-opioid receptors, were grown under conditions that provided a…
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Highly Cited
1992
Highly Cited
1992
Spinal interactions between opioid and noradrenergic agonists in mice: multiplicativity involves delta and alpha-2 receptors.
S. Roerig
,
Sizheng Lei
,
K. Kitto
,
J. Hylden
,
George L. Wilcox
Journal of Pharmacology and Experimental…
1992
Corpus ID: 24028378
The nature of the interaction between spinally administered opioid and alpha-2 agonists was investigated using the substance P…
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Highly Cited
1992
Highly Cited
1992
Whole body and brain distribution of [3H]cyclic [D-Pen2,D-Pen5] enkephalin after intraperitoneal, intravenous, oral and subcutaneous administration.
S. J. Weber
,
D. L. Greene
,
V. Hruby
,
H. Yamamura
,
F. Porreca
,
T. Davis
Journal of Pharmacology and Experimental…
1992
Corpus ID: 22385793
The route of administration of a given drug can have a significant influence upon whole body distribution. The present study…
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Highly Cited
1991
Highly Cited
1991
Characteristics of dose-dependent antagonism by beta-funaltrexamine of the antinociceptive effects of intrathecal mu agonists.
E. Mjanger
,
T. L. Yaksh
Journal of Pharmacology and Experimental…
1991
Corpus ID: 34907989
Using rats with chronic i.t. catheters, dose-response curves were carried out using the hot plate (HP) test for a number of…
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1990
1990
Lack of antinociceptive cross-tolerance between intracerebroventricularly administered beta-endorphin and morphine or DPDPE in mice.
H. H. Suh
,
L. Tseng
Life Science
1990
Corpus ID: 20414313
1988
1988
Conformational determinants of high affinity delta receptor binding of opioid peptides.
C. Keys
,
P. Payne
,
P. Amsterdam
,
L. Toll
,
G. Loew
Molecular Pharmacology
1988
Corpus ID: 21822350
Detailed conformational analysis of linear and cyclic delta-selective opioid peptides was performed in conjunction with computer…
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Highly Cited
1988
Highly Cited
1988
Enkephalins modulate excitatory synaptic transmission in the superficial dorsal horn by acting at μ-opioid receptor sites
S. Jeftinija
Brain Research
1988
Corpus ID: 957938
Highly Cited
1986
Highly Cited
1986
Action at the mu receptor is sufficient to explain the supraspinal analgesic effect of opiates F.G. Fang, H.L. Fields and N.M. Lee, J. Pharmacol. Exp. Ther., 238 (1986) 1039–1044
F. G. Fang
,
H. Fields
,
N. Lee
Pain
1986
Corpus ID: 26169104
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