Involvement of endogenous endothelins in thermal and mechanical inflammatory hyperalgesia in mice
- A. Baamonde, A. Lastra, M. Villazón, J. Bordallo, A. Hidalgo, L. Menéndez
- Biology, MedicineNaunyn-Schmiedeberg's Archives of Pharmacology
- 1 February 2004
The role of ETB receptors ininflammatory pain is further supported and new insights into the participation of ETA receptors in inflammatory hyperalgesia are given.
Sex-related differences in the effects of morphine and stress on visceral pain
Spinal CCL2 and microglial activation are involved in paclitaxel-evoked cold hyperalgesia
Spinal and peripheral analgesic effects of the CB2 cannabinoid receptor agonist AM1241 in two models of bone cancer‐induced pain
- V. Curto-Reyes, S. Llames, A. Hidalgo, L. Menéndez, A. Baamonde
- Medicine, BiologyBritish Journal of Pharmacology
- 1 June 2010
Whether the activation of peripheral or spinal CB2 receptors relieves thermal hyperalgesia and mechanical allodynia in two models of bone cancer pain is studied.
Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation
- A. R. Folgueras, T. Valdes-Sanchez, C. López-Otín
- BiologyProceedings of the National Academy of Sciences
- 22 September 2009
It is reported that MT5-MMP is expressed by CGRP-containing peptidergic nociceptors in dorsal root ganglia and that Mmp24-deficient mice display enhanced sensitivity to noxious thermal stimuli under basal conditions.
Initial thermal heat hypoalgesia and delayed hyperalgesia in a murine model of bone cancer pain
Nociceptive reaction and thermal hyperalgesia induced by local ET-1 in mice: a behavioral and Fos study
- L. Menéndez, A. Lastra, A. Hidalgo, A. Baamonde
- BiologyNaunyn-Schmiedeberg's Archives of Pharmacology
Local ET-1 induces nocifensive behavior and thermal hyperalgesia acting through ETA receptors, and these same receptors seem to be also involved in the amplification of Fos immunoreactivity induced byET-1 under heat stimulus in the dorsal horn neurons.
Unilateral hot plate test: a simple and sensitive method for detecting central and peripheral hyperalgesia in mice
Antidepressant-type effects of endogenous enkephalins protected by systemic RB 101 are mediated by opioid delta and dopamine D1 receptor stimulation.
A Role for Tachykinins in Female Mouse and Rat Reproductive Function1
The data show that tachykinins of both neuronal and nonneuronal origin are differentially expressed in various types of reproductive cells and may play a role in female reproductive function.