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Cyclosporine

Known as: Ciclosporine, Ciclosporin, CyA 
A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (10)

(melle-4)cyclosporinAtopicaIminoralNeoral
Cyclosporine 0.5 MG/ML Ophthalmic Suspension [Restasis]Cyclosporine 25 MG Oral Capsule [Sandimmune]Cyclosporine:MCnc:Pt:Bld:Qn:IACyclosporine:Mass:Pt:Dose:Qn

Broader (3)

Dermatologic AgentsEnzyme InhibitorsImmunosuppressive Agents

Papers overview

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Highly Cited
2007
Highly Cited
2007
Results of an International, Randomized Trial Comparing Glucose Metabolism Disorders and Outcome with Cyclosporine Versus Tacrolimus
DIRECT (Diabetes Incidence after Renal Transplantation: Neoral C2 Monitoring Versus Tacrolimus) was a 6‐month, open‐label… 
Highly Cited
2005
Highly Cited
2005
Incidence of BK with Tacrolimus Versus Cyclosporine and Impact of Preemptive Immunosuppression Reduction
Our purposes were to determine the incidence of BK viruria, viremia or nephropathy with tacrolimus (FK506) versus cyclosporine… 
Highly Cited
2002
Highly Cited
2002
The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors*
Immunosuppressant drugs such as cyclosporin have allowed widespread organ transplantation, but their utility remains limited by… 
Highly Cited
1995
Highly Cited
1995
PLACEBO-CONTROLLED STUDY OF MYCOPHENOLATE MOFETIL COMBINED WITH CYCLOSPORINE AND CORTICOSTEROIDS FOR PREVENTION OF ACUTE REJECTION
Preliminary studies suggested that mycophenolate mofetil (MMF), which inhibits proliferation of T and B cells, may reduce the… 
Highly Cited
1994
Highly Cited
1994
JNK is involved in signal integration during costimulation of T lymphocytes
Highly Cited
1991
Highly Cited
1991
Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers
We previously reported that natural killer cell stimulatory factor (NKSF), a heterodimeric lymphokine purified from the… 
Highly Cited
1986
Highly Cited
1986
Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia.
We treated 93 patients who had acute nonlymphoblastic leukemia in the first remission or chronic myelocytic leukemia in the… 
Highly Cited
1984
Highly Cited
1984
Cyclosporine-associated chronic nephropathy.
We evaluated glomerular filtration in 17 recipients of heart transplants who were treated for 12 months or longer with… 
Highly Cited
1984
Highly Cited
1984
Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset.
Type I diabetes may be an autoimmune disorder, although the evidence is largely circumstantial. The natural history of the… 
Highly Cited
1970
Highly Cited
1970
A Heuristic Algorithm for the n Job, m Machine Sequencing Problem
This paper describes a simple algorithm for the solution of very large sequence problems without the use of a computer. It… 
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