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Cyclosporine

Known as: Ciclosporine, Ciclosporin, CyA 
A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Experimental evidence suggests that cyclosporine, which inhibits the opening of mitochondrial permeability-transition… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Physical inactivity is a global concern, but diverse physical activity measures in use prevent international… Expand
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Highly Cited
1999
Highly Cited
1999
Malignancy is a common and dreaded complication following organ transplantation,,,. The high incidence of neoplasm and its… Expand
Highly Cited
1998
Highly Cited
1998
PURPOSE We established accelerometer count ranges for the Computer Science and Applications, Inc. (CSA) activity monitor… Expand
Review
1997
Review
1997
As targets for the immunosuppressive drugs cyclosporin A and FK506, transcription factors of the NFAT (nuclear factor of… Expand
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Review
1997
Review
1997
Background. Tacrolimus (FK506), a macrolide molecule that potently inhibits the expression of interleukin 2 by T lymphocytes… Expand
Highly Cited
1994
Highly Cited
1994
BACKGROUND There has been no new effective drug therapy for patients with severe ulcerative colitis since corticosteroids were… Expand
Highly Cited
1991
Highly Cited
1991
Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their… Expand
Highly Cited
1986
Highly Cited
1986
We treated 93 patients who had acute nonlymphoblastic leukemia in the first remission or chronic myelocytic leukemia in the… Expand
Highly Cited
1984
Highly Cited
1984
We evaluated glomerular filtration in 17 recipients of heart transplants who were treated for 12 months or longer with… Expand