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Cyclosporine

Known as: Ciclosporine, Ciclosporin, CyA 
A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (10)

(melle-4)cyclosporinAtopicaIminoralNeoral
Cyclosporine 0.5 MG/ML Ophthalmic Suspension [Restasis]Cyclosporine 25 MG Oral Capsule [Sandimmune]Cyclosporine:MCnc:Pt:Bld:Qn:IACyclosporine:Mass:Pt:Dose:Qn

Broader (3)

Dermatologic AgentsEnzyme InhibitorsImmunosuppressive Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Low-dose cyclosporine and mycophenolate mofetil in renal allograft recipients with suboptimal renal function.
BACKGROUND Cyclosporine (CsA) nephrotoxicity can be identified by functional changes and chronic renal damage. CsA-associated… 
Highly Cited
1997
Highly Cited
1997
Characterization and quantification of rat bile phosphatidylcholine by electrospray-tandem mass spectrometry.
Rat bile phosphatidylcholine was structurally characterized and quantified by electrospray mass spectrometry using a triple… 
Highly Cited
1989
Highly Cited
1989
Regulation of human gingival fibroblast growth and synthetic activity by cyclosporine-A in vitro.
Gingival overgrowth is an adverse side-effect seen in a proportion of patients taking cyclosporin-A which indicates that… 
Highly Cited
1987
Highly Cited
1987
Cyclosporin A in rheumatoid arthritis: preliminary clinical results of an open trial.
Twelve patients with refractory rheumatoid arthritis were included in a 1-year open trial of cyclosporin A (CsA), 5 mg/kg/day… 
Highly Cited
1983
Highly Cited
1983
Spontaneous Diabetes Mellitus in the BB/W Rat: Effects of Glucocorticoids, Cyclosporin-A, and Antiserum to Rat Lymphocytes
Combination immunosuppression therapy with long-acting glucocorticoids, cyclosporin-A, and antiserum to rat lymphocytes (ALS… 
Highly Cited
1983
Highly Cited
1983
Selective suppression of an early step in human B cell activation by cyclosporin A
The effect of cyclosporin A (CsA), a fungal metabolite with immunosuppressive properties, on the induction of human B cell… 
Highly Cited
1983
Highly Cited
1983
Marked reduction of DNA antibody production and glomerulopathy in thymulin (FTS-Zn) or cyclosporin A treated (NZB X NZW) F1 mice.
In this study we have evaluated the action of two compounds, cyclosporin A (Cy A) and thymulin (FTS-Zn) in old (NZB X NZW) F1… 
Highly Cited
1981
Highly Cited
1981
T cell growth factor abrogates concanavalin A-induced suppressor cell function
Concanavalin A (Con-A)-induced suppressor T cells were found to respond to T cell growth factor (TCGF) by proliferation. TCGF… 
Highly Cited
1980
Highly Cited
1980
The activity of partially purified leukocytic endogenous mediator in endotoxin-resistant C3H/HeJ mice.
Partially purified LEM was injected into both the endotoxin-resistant C3H/HeJ and the closely related, but endotoxin-responsive… 
Highly Cited
1976
Highly Cited
1976
Properties of adenyl cyclase and cyclic adenosine 3',5'-monophosphate receptor protein-deficient mutants of Escherichia coli
Several spontaneous cya and crp mutants of Escherichia coli have been selected as clones simultaneously resistant to phage lambda… 
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