Cyclosporine

Known as: Ciclosporine, Ciclosporin, CyA 
A natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known… (More)

Topic mentions per year

Topic mentions per year

1938-2017
01000200019382016

Papers overview

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Review
2016
Review
2016
The crucial issue for a better pregnancy outcome in women with autoimmune rheumatic diseases is appropriate planning, with… (More)
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Highly Cited
2010
Highly Cited
2010
Belatacept, a costimulation blocker, may preserve renal function and improve long-term outcomes versus calcineurin inhibitors in… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Experimental evidence suggests that cyclosporine, which inhibits the opening of mitochondrial permeability-transition… (More)
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Highly Cited
2008
Highly Cited
2008
The immunosuppressive action of the calcineurin inhibitor cyclosporine A (CsA) stems from the inhibition of nuclear factor of… (More)
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Highly Cited
2001
Highly Cited
2001
Skeletal muscles adapt to changes in their workload by regulating fibre size by unknown mechanisms. The roles of two signalling… (More)
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Highly Cited
1999
Highly Cited
1999
Malignancy is a common and dreaded complication following organ transplantation. The high incidence of neoplasm and its… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND There has been no new effective drug therapy for patients with severe ulcerative colitis since corticosteroids were… (More)
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Highly Cited
1991
Highly Cited
1991
Although the immediate receptors (immunophilins) of the immunosuppressants cyclosporin A (CsA) and FK506 are distinct, their… (More)
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Highly Cited
1986
Highly Cited
1986
We treated 93 patients who had acute nonlymphoblastic leukemia in the first remission or chronic myelocytic leukemia in the… (More)
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Highly Cited
1984
Highly Cited
1984
We evaluated glomerular filtration in 17 recipients of heart transplants who were treated for 12 months or longer with… (More)
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