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Cyanoketone
Known as:
Androst-5-ene-2-carbonitrile, 17-hydroxy-4,4,17-trimethyl-3-oxo-, (2alpha,17beta)-
, Cyanoketone [Chemical/Ingredient]
2 alpha-Cyano-17 beta-hydroxy-4,4',17 alpha-trimethylandrost-5-ene-3-one. An androstenolone-nitrile compound with steroidogenesis-blocking activity.
National Institutes of Health
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1977
1977
Pregnenolone-binding proteins in the rat adrenal cortex.
B. Kream
,
L. Sauer
Endocrinology
1977
Corpus ID: 11972331
Rat adrenal cortex contains a protein(s) that binds pregnenolone with high affinity. This binding, demonstrated by gel filtration…
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1977
1977
Estimation of pregnenolone synthesis in rat adrenal homogenates: some cofactor requirements: effects of stress, hypophysectomy, cortisone and ACTH.
L. Malendowicz
,
Julian I. Kitay
Endokrinologie
1977
Corpus ID: 6739663
Pregnenolone synthesis was estimated in whole adrenal homogenates incubated in the presence of cyanoketone (2alpha-cyano-4,4…
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1977
1977
A comparison between organomercurial- and progesterone-induced maturation in amphibian oocytes.
A. Pays
,
E. Hubert
,
Jean Brachet
Differentiation; research in biological diversity
1977
Corpus ID: 45732927
1. From the many substances tested, only organomercurials which do not penetrate well into the cells (PHMB, PHMPS, meralluride…
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Highly Cited
1976
Highly Cited
1976
Oocytic meiosis in cultured rat follicles during inhibition of steroidogenesis.
M. Lieberman
,
A. Tsafriri
,
S. Bauminger
,
W. Collins
,
Kurt Ahrén
,
H. R. Lindner
Acta Endocrinologica
1976
Corpus ID: 38875380
Steroid release by cultured Graafian follicles explanted from rat ovaries on the morning of pro-oestrus was measured by…
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Highly Cited
1976
Highly Cited
1976
Progesterone biosynthesis and metabolism by ovarian follicles and isolated oocytes Xenopus laevis.
C. Thibier-Fouchet
,
O. Mulner
,
R. Ozon
Biology of Reproduction
1976
Corpus ID: 32961013
Ovarian follicles of Xen opus laevis exposed to exogenous radioactive pregnenolone have been observed to synthesize radioactive…
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1976
1976
CYANOKETONE-INDUCED INHIBITION OF ADRENAL 3β-HYDROXY-Δ5-STEROID OXIDOREDUCTASE ACTIVITY IN FEMALE AND MALE RATS IN VITRO
S. Gustafsson
1976
Corpus ID: 73040150
The inhibition of adrenal 3beta-hydroxy-delta5-steroid oxidoreductase activity was studied in vitro 24 h after a single injection…
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1973
1973
Sex-dependent differences in derangements of biliary-steroid-excretion patterns produced by cyanoketone in rats.
R. Begue
,
Allen S. Goldman
,
Jan-Åke Gustafsson
,
S. Gustafsson
European Journal of Biochemistry
1973
Corpus ID: 44473524
Intramuscular injections of 25 mg/kg body weight of 2α-cyano-4,4,17α-trimethyl-5-androsten-17β-ol-3-one (cyanoketone) produces…
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1971
1971
Inhibition of steroidogenesis by cyanoketone.
C. D. di Prisco
,
G. Materazzi
,
B. Scattolini
Gynecologic Investigation
1971
Corpus ID: 29265486
The effect of cyanoketone on some steps of steroidogenesis has been studied on testicular and adrenal tissue of male Wistar rats…
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1971
1971
Stimulation of pregnenolone synthesis by ACTH in rat adrenal sections.
R. V. Farese
Endocrinology
1971
Corpus ID: 39030495
Pregnenolone accumulates in rat adrenal sections incubated in the presence of cyanoketone, and it is thus possible to directly…
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1970
1970
Follicular processes in ovulation.
P. Rondell
Federation proceedings
1970
Corpus ID: 6336067
The follicular processes involved in ovulation are examined. Previous studies of ovarian functions have established that…
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