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Cotinine

Known as: (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone, Cotinine [Chemical/Ingredient], S-(-)-Cotinine 
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It… 
National Institutes of Health

Related topics

Related topics

20 relations
Cotinine FumarateCotinine cutoff:MCnc:Pt:Urine:QnCotinine/Creatinine:MRto:Pt:Urine:QnCotinine:MCnc:Pt:Ser/Plas:Qn

Broader (1)

Indicators and Reagents

Narrower (3)

N-hydroxymethylnorcotininehydroxycotininenorcotinine

Papers overview

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Review
2005
Review
2005
Time to review the value of imaging after urinary tract infection in infants
Commentary on the paper by Spencer et al (see page670) Passive smoke exposure (PSE) is carcinogenic, linked to cardiovascular… 
2005
2005
DNA adducts in human placenta in relation to tobacco smoke exposure and plasma antioxidant status
The DNA adduct 8-hydroxy-2′-deoxyguanosine (8-OHdG) has been widely used as a biomarker for oxidative stress. Bulky DNA adducts… 
2004
2004
Active and passive tobacco smoke exposure: a comparison of maternal and child hair cotinine levels.
The objective of this study was to compare tobacco smoke exposure in mothers and their healthy children less than 3 years old… 
2000
2000
Platelet monoamine oxidase B activity is inversely associated with plasma cotinine concentration.
Cigarette smoke but not nicotine inhibits irreversibly platelet monoamine oxidase B (MAO-B) activity. Current smokers have… 
1993
1993
Hair analysis as a marker for fetal exposure to maternal smoking.
To the Editor: Maternal cigarette smoking during pregnancy is associated with fetal risks in the short and long term1,2. Any… 
1993
1993
SUBCHRONIC INHALATION STUDY IN RATS USING AGED AND DILUTED SIDESTREAM SMOKE FROM A REFERENCE CIGARETTE
AbstractMale Sprague-Dawley rats were exposed 6 hr/day, 5 days/week for up to 13 weeks to aged and diluted sidestream smoke (ADSS… 
1991
1991
Trapping of reactive intermediates by incorporation of 14C-sodium cyanide during microsomal oxidation.
It has long been known that nicotine is metabolized to the corresponding amide cotinine (McKennis et al., 1957). The metabolism… 
1986
1986
Effects of smoking on inflammatory mediators and their relationship to pulmonary dysfunction.
Study populations of 170 male smokers and 170 age- and sex-matched nonsmokers were used to determine the effects of cigarette… 
1985
1985
Evaluation of general practitioners' use of a smoking intervention programme.
A study was made of a smoking cessation programme in a four-man general practice to determine the efficacy of general… 
1976
1976
Disposition of nicotine in the rat after intravenous administration.
The pharmacokinetics of 14C-labeled nicotine were studied in male Fischer-344 rats following the i.v. administration of a single…