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Cotinine

Known as: (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone, Cotinine [Chemical/Ingredient], S-(-)-Cotinine 
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It… 
National Institutes of Health

Related topics

Related topics

20 relations
Cotinine FumarateCotinine cutoff:MCnc:Pt:Urine:QnCotinine/Creatinine:MRto:Pt:Urine:QnCotinine:MCnc:Pt:Ser/Plas:Qn

Broader (1)

Indicators and Reagents

Narrower (3)

N-hydroxymethylnorcotininehydroxycotininenorcotinine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Glucuronidation of nicotine and cotinine by UGT2B10: loss of function by the UGT2B10 Codon 67 (Asp>Tyr) polymorphism.
Nicotine, the major addicting agent in tobacco and tobacco smoke, undergoes a complex metabolic pathway, with approximately 22… 
Highly Cited
2005
Highly Cited
2005
A randomized trial of nicotine enemas for active ulcerative colitis.
Highly Cited
1996
Highly Cited
1996
Effects of smoking cessation on insulin and cardiovascular risk factors – a controlled study of 4 months' duration
Objectives. To investigate the effects on serum lipids, plasma fibrinogen, plasma insulin, plasma C‐peptide and blood glucose, of… 
Highly Cited
1994
Highly Cited
1994
Individualized smoking cessation counseling during prenatal and early postnatal care.
Highly Cited
1989
Highly Cited
1989
Ecology of passive smoking by young infants.
Highly Cited
1987
Highly Cited
1987
The direct barbituric acid assay for nicotine metabolites in urine: a simple colorimetric test for the routine assessment of smoking status and cigarette smoke intake.
Highly Cited
1983
Highly Cited
1983
Nocotine dependence in cigarette smoking: An empirically-based, multivariate model
Highly Cited
1979
Highly Cited
1979
Nicotinic cholinergic receptors in brain synaptosomes
Highly Cited
1978
Highly Cited
1978
Gas-liquid chromatographic determination of nicotine and cotinine in plasma.
We report a procedure for determining nicotine and cotinine in plasma. Nicotine is extracted from 1 ml of plasma with diethyl… 
Highly Cited
1975
Highly Cited
1975
NICOTINE ABSORPTION BY WORKERS HARVESTING GREEN TOBACCO
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