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Cotinine

Known as: (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone, Cotinine [Chemical/Ingredient], S-(-)-Cotinine 
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It… 
National Institutes of Health

Related topics

Related topics

20 relations
Cotinine FumarateCotinine cutoff:MCnc:Pt:Urine:QnCotinine/Creatinine:MRto:Pt:Urine:QnCotinine:MCnc:Pt:Ser/Plas:Qn

Broader (1)

Indicators and Reagents

Narrower (3)

N-hydroxymethylnorcotininehydroxycotininenorcotinine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
A randomized trial of nicotine enemas for active ulcerative colitis.
Highly Cited
2004
Highly Cited
2004
Subsets of acetylcholine-stimulated 86Rb+ efflux and [125I]-epibatidine binding sites in C57BL/6 mouse brain are differentially affected by chronic nicotine treatment
Highly Cited
2001
Highly Cited
2001
Novel liquid chromatographic-tandem mass spectrometric methods using silica columns and aqueous-organic mobile phases for quantitative analysis of polar ionic analytes in biological fluids.
Highly Cited
1994
Highly Cited
1994
Meconium analysis to assess fetal exposure to nicotine by active and passive maternal smoking.
Highly Cited
1993
Highly Cited
1993
Smoking cessation, clonidine, and vulnerability to nicotine among dependent smokers
This study examines the efficacy of clonidine in smoking cessation and the influence of gender, history of major depression, and… 
Highly Cited
1992
Highly Cited
1992
Smoking and decreased fertilisation rates in vitro
Highly Cited
1985
Highly Cited
1985
Analytical cigarette yields as predictors of smoke bioavailability.
Highly Cited
1979
Highly Cited
1979
Cigarette smoking as a dependence process.
ed from Turner, J.A.M.; Sillett, R.W.; and McNichol, M.W. Effect of carboxyhaemoglobin and plasma nicotine concentrations in… 
Highly Cited
1978
Highly Cited
1978
Gas-liquid chromatographic determination of nicotine and cotinine in plasma.
We report a procedure for determining nicotine and cotinine in plasma. Nicotine is extracted from 1 ml of plasma with diethyl… 
Highly Cited
1971
Highly Cited
1971
Enzymic oxidation of (-)-nicotine by guinea-pig tissues in vitro.
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