Cotinine

Known as: (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone, Cotinine [Chemical/Ingredient], S-(-)-Cotinine 
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2018
010020019592018

Papers overview

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Highly Cited
2013
Highly Cited
2013
CONTEXT Electronic cigarettes (e-cigarettes) are becoming increasingly popular yet their effects on health remain unknown… (More)
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Highly Cited
2002
Highly Cited
2002
Cigarette smoking is the foremost modifiable risk factor for adverse pregnancy outcomes. Nicotine is a suspected fetal… (More)
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Highly Cited
2000
Highly Cited
2000
The authors collected by mail self-reported data on smoking habits and saliva samples that were analyzed for cotinine… (More)
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Highly Cited
1999
Highly Cited
1999
We previously reported that the metabolism of cotinine, the proximate metabolite of nicotine, is significantly slower in black… (More)
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Highly Cited
1998
Highly Cited
1998
Although during pregnancy there is a better correlation between maternal serum cotinine concentration and adverse outcome than… (More)
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Highly Cited
1994
Highly Cited
1994
OBJECTIVES (1) To determine the disposition kinetics of nicotine and cotinine, including the fractional conversion of nicotine to… (More)
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Highly Cited
1993
Highly Cited
1993
Published research suggests that smokers metabolize nicotine and its major metabolite cotinine more rapidly than nonsmokers. To… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Although widely used in epidemiological studies, self-report has been shown to underestimate the prevalence of… (More)
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Highly Cited
1990
Highly Cited
1990
A rapid method is described for the simultaneous measurement of nicotine and cotinine in biological fluids using capillary column… (More)
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Highly Cited
1981
Highly Cited
1981
Improved methods have been developed for the determination of nicotine and its major metabolite, cotinine, in blood, plasma, and… (More)
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