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N-hydroxymethylnorcotinine

Known as: 5-(3'-pyridyl)-1-hydroxymethyl-2-pyrrolidone, N-(hydroxymethyl)norcotinine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cotinine
analogs & derivatives

Papers overview

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Highly Cited
2006
Highly Cited
2006
Inactivation of CYP2A6 and CYP2A13 during Nicotine Metabolism
Nicotine is the major addictive agent in tobacco. The primary catalyst of nicotine metabolism in humans is CYP2A6. However, the… 
2005
2005
Identification of N-(hydroxymethyl) norcotinine as a major product of cytochrome P450 2A6, but not cytochrome P450 2A13-catalyzed cotinine metabolism.
Cotinine formation is the major pathway of nicotine metabolism in smokers, and the primary pathway of cotinine metabolism is… 
Highly Cited
1999
Highly Cited
1999
Characterization of multiple products of cytochrome P450 2A6-catalyzed cotinine metabolism.
The primary metabolite of nicotine in smokers is cotinine. Cotinine is further metabolized to trans-3'-hydroxycotinine, the major… 
1994
1994
N-hydroxymethylnorcotinine, a new primary in vitro metabolite of cotinine.
  • Y. LiJ. Gorrod
  • Xenobiotica; the fate of foreign compounds in…
  • 1994
  • Corpus ID: 23020216
1. N-Hydroxymethylnorcotinine; 5-(3'-pyridyl)-1-hydroxymethyl-pyrrolidone-2, was found as a new primary metabolite of cotinine in… 
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