Cortactin

Known as: Cortactin [Chemical/Ingredient] 
A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Src kinase mediates growth factor signaling and causes oncogenic transformation, which includes dramatic changes in the actin… (More)
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Highly Cited
2007
Highly Cited
2007
Invadopodia are branched actin-rich structures associated with extracellular matrix (ECM) degradation that collectively form the… (More)
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Highly Cited
2007
Highly Cited
2007
Histone deacetylase 6 (HDAC6) is a tubulin-specific deacetylase that regulates microtubule-dependent cell movement. In this study… (More)
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Review
2006
Review
2006
Cortactin, an actin filament-binding protein and target of multiple kinases, has emerged as a central element connecting… (More)
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Highly Cited
2005
Highly Cited
2005
During clathrin-mediated endocytosis, membrane scission marks the isolation of a cargo-laden clathrin-coated pit (CCP) from the… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Lamellipodial protrusion, which is the first step in cell movement, is driven by actin assembly and requires activity… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Dynamic actin assembly is required for diverse cellular processes and often involves activation of Arp2/3 complex… (More)
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Highly Cited
2001
Highly Cited
2001
Cortactin is a c-src substrate associated with sites of dynamic actin assembly at the leading edge of migrating cells. We… (More)
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Highly Cited
2001
Highly Cited
2001
Cortactin, a filamentous actin (F-actin)-associated protein and prominent substrate of Src, is implicated in progression of… (More)
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Highly Cited
1993
Highly Cited
1993
Two related cellular proteins, p80 and p85 (cortactin), become phosphorylated on tyrosine in pp60src-transformed cells and in… (More)
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