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CTTN gene

Known as: CTTN, ONCOGENE EMS1, Cortactin Gene 
This gene plays a role in epithelial cytoskeletal organization and in cellular adhesion.
National Institutes of Health

Related topics

Related topics

6 relations
CTTN protein, humanCytoskeletal ModelingRegulation of Cell ShapeSquamous Cell Breast Carcinoma

Narrower (2)

CTTN wt AlleleCortactin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Src and fibroblast growth factor 2 independently regulate signaling and gene expression induced by experimental injury to intact articular cartilage.
OBJECTIVE To investigate whether cartilage injury activates protein tyrosine kinases distinct from fibroblast growth factor (FGF… 
2012
2012
Regulation of late endosomal/lysosomal maturation and trafficking by cortactin affects Golgi morphology
Cortactin is a branched actin regulator and tumor‐overexpressed protein that promotes vesicular trafficking at a variety of… 
Highly Cited
2011
Highly Cited
2011
Liprin-α1 regulates breast cancer cell invasion by affecting cell motility, invadopodia and extracellular matrix degradation
Migration of cells and degradation of the extracellular matrix (ECM) are required for efficient tumor cell invasion, but the… 
Highly Cited
2007
Highly Cited
2007
Regulation of Hyperoxia-induced NADPH Oxidase Activation in Human Lung Endothelial Cells by the Actin Cytoskeleton and Cortactin*
Although the actin cytoskeleton has been implicated in the control of NADPH oxidase in phagocytosis, very little is known about… 
Highly Cited
2005
Highly Cited
2005
The Coiled-coil Domain Is Required for HS1 to Bind to F-actin and Activate Arp2/3 Complex*
HS1 (hematopoietic lineage cell-specific protein 1), a substrate of protein tyrosine kinases in lymphocytes, binds to F-actin… 
2004
2004
BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration.
Rho GTPases control cell dynamics during growth and development. They are activated by guanine nucleotide exchange factors and… 
Highly Cited
2003
Highly Cited
2003
Cooperative Roles of Fyn and Cortactin in Cell Migration of Metastatic Murine Melanoma*
Src family kinases are major regulators of various integrin-mediated biological processes, although their functional roles and… 
Highly Cited
1994
Highly Cited
1994
Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin.
The initiation of maximal DNA synthesis by fibroblast growth factor (FGF)-1 requires the presence of the growth factor during the… 
Review
1994
Review
1994
Identification of major tyrosine-phosphorylated proteins in Csk-deficient cells.
Csk is a non-receptor protein-tyrosine kinase that acts as a negative regulator of Src family tyrosine kinases. Csk-deficient… 
Review
1993
Review
1993
Chromosome 11q13 abnormalities in human breast cancer.
Amplification of markers centred on band q13 of human chromosome 11 is a consistent feature in a subset of oestrogen receptor… 
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