CTTN protein, human

Known as: Amplaxin, Oncogene EMS1, EMS1 
Src substrate cortactin (550 aa, ~62 kDa) is encoded by the human CTTN gene. This protein is involved in the regulation of both the interactions… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2018
05101519792018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The mechanisms regulating invadopodium… (More)
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2009
2009
We have shown earlier that overexpression of Calreticulin (CRT) contributed to a poor prognosis for patients with esophageal… (More)
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Highly Cited
2008
Highly Cited
2008
Sexual reproduction requires the specification of cells with distinct fates in plants and animals. The EMS1 (also known as EXS… (More)
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2008
2008
Gene amplifications and deletions are frequent in head and neck squamous cell carcinomas (SCC) but the association of these… (More)
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Highly Cited
2006
Highly Cited
2006
Alternative splicing is a mechanism for increasing protein diversity by excluding or including exons during post-transcriptional… (More)
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Highly Cited
2004
Highly Cited
2004
The Arp2/3 complex can be independently activated to initiate actin polymerization by the VCA domain of WASP family members and… (More)
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Highly Cited
2003
Highly Cited
2003
Growth factor regulation of the cortical actin cytoskeleton is fundamental to a wide variety of cellular processes. The cortical… (More)
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Highly Cited
1999
Highly Cited
1999
The structural characteristics of EMS1 (human cortactin) suggest that it may link signaling events to reorganization of the actin… (More)
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Highly Cited
1998
Highly Cited
1998
Small GTPases of the Rho family regulate signaling pathways that control actin cytoskeletal structures. In Swiss 3T3 cells, RhoA… (More)
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Highly Cited
1992
Highly Cited
1992
Amplification of the chromosome 11q13 region is frequently found in human breast cancer and in squamous cell carcinomas of the… (More)
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