Conotoxin

Known as: Conotoxins, Conotoxins [Chemical/Ingredient] 
Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly… (More)
National Institutes of Health

Related topics

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48 relations

Narrower (37)

AnIA protein, Conus anemonealpha-Conotoxinsalpha-conotoxin BuIA, Conus bullatusalpha-conotoxin GID, Conus geographus
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Calcium Channel BlockersConus genusIn BloodProcess of secretion
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Broader (2)

Marine ToxinsNeurotoxins

Papers overview

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Highly Cited
2014
Highly Cited
2014
iCTX-Type: A Sequence-Based Predictor for Identifying the Types of Conotoxins in Targeting Ion Channels
Conotoxins are small disulfide-rich neurotoxic peptides, which can bind to ion channels with very high specificity and modulate… (More)
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Highly Cited
1998
Highly Cited
1998
alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release.
Neuronal nicotinic acetylcholine receptors (nAChRs) with putative alpha3 beta4-subunits have been implicated in the mediation of… (More)
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Highly Cited
1997
Highly Cited
1997
Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes.
Activation of presynaptic nicotinic acetylcholine receptors (nAChRs) can induce the release of neurotransmitters such as dopamine… (More)
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Highly Cited
1996
Highly Cited
1996
A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors.
We have isolated a 16-amino acid peptide from the venom of the marine snail Conus magus which potently blocks nicotinic… (More)
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Highly Cited
1996
Highly Cited
1996
Inhibition of calcium channels in rat central and peripheral neurons by omega-conotoxin MVIIC.
Inhibition of voltage-dependent calcium channels by omega-conotoxin MVIIC (omega-CTx-MVIIC) was studied in various types of rat… (More)
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Highly Cited
1993
Highly Cited
1993
Nifedipine- and omega-conotoxin-sensitive Ca2+ conductances in guinea-pig substantia nigra pars compacta neurones.
1. The membrane properties of substantia nigra pars compacta (SNc) neurones were recorded in guinea-pig in vitro brain slices. 2… (More)
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Highly Cited
1992
Highly Cited
1992
HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.
Monoclonal antibodies were produced that recognize a membrane protein of 35,000 Da (p35) expressed in brain and adrenal medulla… (More)
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Highly Cited
1992
Highly Cited
1992
Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel.
Of the four major types of Ca channel described in vertebrate cells (designated T, L, N, and P), N-type Ca channels are unique in… (More)
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Highly Cited
1987
Highly Cited
1987
Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle.
Blockade of Ca2+ channels by omega-conotoxin GVIA, a 27 amino acid peptide from the venom of the marine snail Conus geographus… (More)
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Highly Cited
1987
Highly Cited
1987
Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using omega-conotoxin from Conus magus venom.
The omega-conotoxins from the venom of fish-hunting cone snails are probably the most useful of presently available ligands for… (More)
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