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Concanavalin A

Known as: Con-A, concanavalin, Concanavalin A [Chemical/Ingredient] 
A mannose-binding lectin originally isolated from jack-bean, Canavalia ensiformis. Concanavalin A is a potent lymphocyte mitogen and a stimulator of… 
National Institutes of Health

Related topics

Related topics

16 relations
In BloodProcess of secretionReceptors, Concanavalin Aagonists

Broader (3)

LectinMitogensPlant Proteins

Narrower (5)

apoconcanavalin Abiotinylconcanavalin Amannosyl(1-2)-mannosyl methyl ester concanavalin A complexsuccinylconcanavalin A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1981
1981
Comparison of a simplified whole blood and isolated lymphocyte stimulation technique.
Whole blood and isolated lymphocyte stimulation in healthy men were compared utilizing PHA, ConA, and PWM. Dose response curves… 
Highly Cited
1978
Highly Cited
1978
Chimeric toxins: toxic, disulfide-linked conjugate of concanavalin A with fragment A from diphtheria toxin.
A disulfide-linked conjugate of concanavalin A (Con A) and fragment A from diphtheria toxin has been synthesized and shown to be… 
Highly Cited
1977
Highly Cited
1977
Human suppressor T cells induced by concanavalin A: suppressor T cells belong to distinctive T cell subclasses.
Human peripheral blood lymphocytes were stimulated by concanavalin A (Con A) and then evaluated by their suppressive activity for… 
Highly Cited
1977
Highly Cited
1977
Comparative serological and cutaneous reactivity of candidal cytoplasmic proteins and mannan separated by affinity for concanavalin A
Yeast-form Candida albicans cells were disrupted for 1.5 min in a Braun homogenizer and centrifuged at 100,000 X g. The… 
Highly Cited
1977
Highly Cited
1977
Enhancement of the PGE1 response of macrophages by concanavalin A and colchicine.
The effect of concanavalin A (Con A) and colchicine on the prostaglandin E1 (PGE1)-mediated cyclic AMP generation in rat… 
Highly Cited
1975
Highly Cited
1975
Factors affecting the molecular structure and the agglutinating ability of concanavalin A and other lectins.
Ultracentrifugation analyses were performed on lectins under varying conditions of pH, ionic strength and temperature. It has… 
Highly Cited
1974
Highly Cited
1974
Agglutination of Trypanosoma cruzi by concanavalin A.
SYNOPSIS Epimastigotes of Trypanosoma cruzi obtained in culture agglutinate readily with low concentrations of concanavalin A… 
Highly Cited
1974
Highly Cited
1974
Ultrastructural localization of surface receptors for concanavalin A on rabbit spermatozoa.
The distribution of Concanavalin A (Con A) receptors on the surface of ejaculated and capacitated rabbit spermatozoa was… 
Highly Cited
1973
Highly Cited
1973
Selective activation of chicken T lymphocytes by concanavalin A.
In vitro response to Con A of chicken spleen lymphocytes was reduced by thymectomy carried out at hatching and completed by… 
1970
1970
Glutaraldehyde-insolubilized concanavalin A: an adsorbent for the specific isolation of polysaccharides and glycoproteins.
The use of water-insoluble polymers composed of or containing covalently bound biologically active substances such as antigens…