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Concanavalin A

Known as: Con-A, concanavalin, Concanavalin A [Chemical/Ingredient] 
A mannose-binding lectin originally isolated from jack-bean, Canavalia ensiformis. Concanavalin A is a potent lymphocyte mitogen and a stimulator of… 
National Institutes of Health

Related topics

Related topics

16 relations
In BloodProcess of secretionReceptors, Concanavalin Aagonists

Broader (3)

LectinMitogensPlant Proteins

Narrower (5)

apoconcanavalin Abiotinylconcanavalin Amannosyl(1-2)-mannosyl methyl ester concanavalin A complexsuccinylconcanavalin A

Papers overview

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2005
2005
A novel artemisinin derivative, 3-(12-β-artemisininoxy) phenoxyl succinic acid (SM735), mediates immunosuppressive effects in vitro and in vivo
AbstractAim:To study the immunosuppressive activity of SM735 {[3 -(12-β-artemisininoxy)] phenoxyl succinic acid}, a synthetic… 
Highly Cited
1987
Highly Cited
1987
Distribution of substance P receptors on murine spleen and Peyer's patch T and B cells.
Previous studies have demonstrated that the sensory neuropeptide substance P (SP) can modulate immune responses in vitro. Work… 
Highly Cited
1985
Highly Cited
1985
A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A.
Antigen or concanavalin A activation of a murine T-cell hybrid specific for pigeon cytochrome c and restricted to the Ek alpha:Ek… 
Highly Cited
1981
Highly Cited
1981
T cell growth factor abrogates concanavalin A-induced suppressor cell function
Concanavalin A (Con-A)-induced suppressor T cells were found to respond to T cell growth factor (TCGF) by proliferation. TCGF… 
Highly Cited
1978
Highly Cited
1978
Chimeric toxins: toxic, disulfide-linked conjugate of concanavalin A with fragment A from diphtheria toxin.
A disulfide-linked conjugate of concanavalin A (Con A) and fragment A from diphtheria toxin has been synthesized and shown to be… 
Highly Cited
1977
Highly Cited
1977
Human suppressor T cells induced by concanavalin A: suppressor T cells belong to distinctive T cell subclasses.
Human peripheral blood lymphocytes were stimulated by concanavalin A (Con A) and then evaluated by their suppressive activity for… 
Highly Cited
1975
Highly Cited
1975
Modulation of lymphocyte receptor mobility by locally bound concanavalin A.
Binding of concanavalin A (con A) to the lymphocyte surface at room temperature leads to restriction of the mobility of a variety… 
Highly Cited
1975
Highly Cited
1975
Local anesthetics affect transmembrane cytoskeletal control of mobility and distribution of cell surface receptors.
Tertiary amine local anesthetics facilitated concanavalin A-induced redistribution of lectin receptors on murine BALB/3T3 cells… 
Highly Cited
1974
Highly Cited
1974
Agglutination of Trypanosoma cruzi by concanavalin A.
SYNOPSIS Epimastigotes of Trypanosoma cruzi obtained in culture agglutinate readily with low concentrations of concanavalin A… 
Highly Cited
1974
Highly Cited
1974
Receptor mobility and the mechanism of cell-cell binding induced by concanavalin A.
The cell-cell binding induced by concanavalin A between single cells has been analyzed by use of cells attached to nylon fibers…