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Concanavalin A

Known as: Con-A, concanavalin, Concanavalin A [Chemical/Ingredient] 
A mannose-binding lectin originally isolated from jack-bean, Canavalia ensiformis. Concanavalin A is a potent lymphocyte mitogen and a stimulator of… 
National Institutes of Health

Related topics

Related topics

16 relations
In BloodProcess of secretionReceptors, Concanavalin Aagonists

Broader (3)

LectinMitogensPlant Proteins

Narrower (5)

apoconcanavalin Abiotinylconcanavalin Amannosyl(1-2)-mannosyl methyl ester concanavalin A complexsuccinylconcanavalin A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1989
Highly Cited
1989
Cytotactin and its proteoglycan ligand mark structural and functional boundaries in somatosensory cortex of the early postnatal mouse.
Highly Cited
1985
Highly Cited
1985
Potential role for a guanine nucleotide regulatory protein in chemoattractant receptor mediated polyphosphoinositide metabolism, Ca++ mobilization and cellular responses by leukocytes.
Highly Cited
1982
Highly Cited
1982
Culture from mouse bone marrow of a subclass of mast cells possessing a distinct chondroitin sulfate proteoglycan with glycosaminoglycans rich in N-acetylgalactosamine-4,6-disulfate.
Review
1982
Review
1982
Polyclonal B-cell activators in the study of the regulation of immunoglobulin synthesis in the human system.
Highly Cited
1975
Highly Cited
1975
Fractionation of glycopeptides by affinity column chromatography on concanavalin A-sepharose.
Using [3H]-labeled oligosaccharides, we found that the presence of at least two alpha-mannosyl residues with free hydroxyl groups… 
Highly Cited
1975
Highly Cited
1975
Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamine--glycoprotein N-acetylglucosaminyltransferase activity.
Several clones of Chinese hamster ovary cells resistant to the cytotoxicity of the phytohemagglutinin from Phaseolus vulgaris… 
Highly Cited
1973
Highly Cited
1973
Insulin-like activity of concanavalin A and wheat germ agglutinin--direct interactions with insulin receptors.
Concanavalin A and wheat germ agglutinin are as effective as insulin in enhancing the rate of glucose transport and in inhibiting… 
Highly Cited
1972
Highly Cited
1972
Topography of membrane concanavalin A sites modified by proteolysis.
The topographic distribution of membrane Con A sites becomes more clustered after treatment with proteolytic enzymes. The… 
Highly Cited
1972
Highly Cited
1972
Functional heterogeneity of murine lymphoid cells. I. Responsiveness to and surface binding of concanavalin A and phytohemagglutinin.
These results are discussed in terms of heterogeneity of mouse lymphoid cell populations and of the complex requirements for… 
Highly Cited
1971
Highly Cited
1971
Difference in topology of normal and tumour cell membranes shown by different surface distributions of ferritin-conjugated concanavalin A.
THE observations of Burger and Goldberg1 on the differential agglutinability of malignant cells by the saccharide-binding protein… 
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