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A Controlled Clinical Trial of E5 Murine Monoclonal IgM Antibody to Endotoxin in the Treatment of Gram-Negative Sepsis
TLDR
Treatment with E5 antiendotoxin antibody appears safe and reduces mortality and enhances the resolution of organ failure among patients with gram-negative sepsis who are not in shock when treated.
Blastomycosis in patients with the acquired immunodeficiency syndrome.
TLDR
Blastomycosis is a late and frequently fatal infectious complication in a few patients with AIDS, and it is associated with a high early mortality.
Clinical and laboratory characteristics of Achromobacter xylosoxidans infection
TLDR
The clinical and laboratory characteristics of A. xylosoxidans are presented and the organism exists in a water environment and may be confused with Pseudomonas species.
Fungal and Yeast Infections of the Central Nervous System: A CLINICAL REVIEW
TLDR
In the past 20 years, there has been a marked increase in the number of reported cases of meningitis and brain abscess due to fungi and yeasts; but the increase can also be attributed to a growing pool of severely compromised hosts, many of whom are undergoing treatment with adrenal glucocorticoids or immunosuppressive agents.
Corynebacterium equi infection complicating neoplastic disease.
TLDR
Corynebacterium equi, a soil-residing diphtheroid pathogenic in horses, swine and cows, caused pulmonary infection with bacteremia in two patients with lymphomas, and one of the patients reported here was successfully treated with erythromycin, tetracycline, and surgery.
Imipenem resistance in Enterobacter.
Blood cultures obtained on two separate occasions from a 37-year-old male who received multiple antibiotics (including imipenem) for treatment of repeated episodes of intraabdominal abscesses and
Comparative serological and cutaneous reactivity of candidal cytoplasmic proteins and mannan separated by affinity for concanavalin A
TLDR
The comparative ability of candidal proteins and cell wall-derived mannan to elicit skin test reactions in guinea pigs sensitized by infection or with formaldehyde-killed yeast was studied.
Vibrio alginolyticus infections in humans
Two clinical isolates of Vibrio alginolyticus from New Jersey are reported, one from a mixed stump infection and the other grown in pure culture from the conjunctival discharge of a man with
Seizure propensity with imipenem.
TLDR
The potent activity of imipenem therapy against bacteria, allowing for a clinical dose of only 2 g/d, is unfortunately offset by its higher propensity to induce neurologic symptoms in humans and mice at much smaller doses than would therapy with penicillin G or the cephalosporins, such as cefotaxime.
Serum levels of arabinitol in the detection of invasive candidiasis in animals and humans.
TLDR
The data indicate that an elevated level of arabinitol in the serum of a patient without renal disease is suggestive of invasive candidiasis, but normal serum levels do not contradict the diagnosis.
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