Complement deficiency

Known as: complement deficiencies, deficiency complement 
A broad classification for rare genetic disorders with mostly autosomal recessive patterns of inheritance. They are caused by the ineffective or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1961-2018
0102019612018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Complement component C5 is crucial for experimental animal inflammatory tissue damage; however, its involvement in human… (More)
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Highly Cited
2006
Highly Cited
2006
Lectin pathway activation of C3 is known to involve target recognition by mannan-binding lectin (MBL) or ficolins and generation… (More)
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2002
2002
Collagen-induced arthritis (CIA) is an experimental animal model of human rheumatoid arthritis being characterized by synovitis… (More)
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2001
2001
Deficiency in the classical pathway complement components displays a hierarchical association with the development of systemic… (More)
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Highly Cited
2000
Highly Cited
2000
The strongest susceptibility genes for the development of systemic lupus erythematosus (SLE) in humans are null mutants of… (More)
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Highly Cited
2000
Highly Cited
2000
In January 2005, a tetravalent meningococcal polysaccharide-protein conjugate vaccine ([MCV4] Menactra, manufactured by Sanofi… (More)
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Highly Cited
1998
Highly Cited
1998
The role of complement in the maintenance of self-tolerance has been examined in two models: an immunoglobulin transgenic model… (More)
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1998
1998
This study reports on six cases of deficiency in the human complement regulatory protein Factor H (FH) in the context of an acute… (More)
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Highly Cited
1997
Highly Cited
1997
Complete deficiency of C1q is almost invariably associated with the development of systemic lupus erythematosus. It has been… (More)
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1994
1994
Nongroupable meningococci or bacteria related to the genus Neisseria rarely cause meningitis. Complement deficiency has been… (More)
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